The information capacity of DNA double-crossover (DX) tiles was successfully increased beyond a binary representation to higher base representations. By controlling the length and the position of DNA hairpins on the DX tile, ternary and senary (base-3 and base-6) digit representations were realized and verified by atomic force microscopy. Also, normal mode analysis was carried out to study the mechanical characteristics of each structure.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1088/0957-4484/25/10/105601 | DOI Listing |
Anal Chem
August 2024
Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.
Toxics
February 2024
Department of Environmental Safety, Institute of Aquaculture and Environmental Safety, Hungarian University of Agriculture and Life Sciences, 1 Páter Károly u., 2100 Gödöllő, Hungary.
Xenobiotics never appear as single, isolated substances in the environment but instead as multi-component mixtures. However, our understanding of the ecotoxicology of mixtures is far from sufficient. In this study, three active pharmaceutical ingredients (carbamazepine, diclofenac, and ibuprofen) and three pesticides (S-metolachlor, terbuthylazine, and tebuconazole) from the most frequently detected emerging micropollutants were examined for their acute cytotoxicity, both individually and in combination, by bioluminescence inhibition in (NRRL B-11177).
View Article and Find Full Text PDFJ Biol Chem
September 2023
Department of Molecular Biology and Biochemistry, University of California, Irvine, California, USA. Electronic address:
Human cytochrome P450 3A4 (CYP3A4) is a major drug-metabolizing enzyme that shows extreme substrate promiscuity. Moreover, its large and malleable active site can simultaneously accommodate several substrate molecules of the same or different nature, which may lead to cooperative binding and allosteric behavior. Due to difficulty of crystallization of CYP3A4-substrate complexes, it remains unknown how multiple substrates can arrange in the active site.
View Article and Find Full Text PDFJ Mol Graph Model
November 2021
Centre for Molecular Modelling, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500007, Telangana State, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, U. P., India; Advanced Computation and Data Sciences Division, CSIR-North East Institute of Science and Technology, Jorhat, 785006, Assam, India. Electronic address:
Human cell membranes consist of various lipids that are essential for their structure and function. It typically comprises phosphatidylcholine (POPC), phosphatidylethanolamine (POPE), phosphatidylserine (POPS), sphingomyelin (PSM), and cholesterol (CHL). Several experimental and computational techniques have been employed to characterize the composition of human cell membranes, however, CHL enriched membrane is still not clearly understood through these techniques.
View Article and Find Full Text PDFACS Comb Sci
December 2020
Advanced Materials Processing and Analysis Center Department of Materials Science and Engineering, University of Central Florida, Orlando, Florida 32816, United States.
Relative role of enthalpy and entropy in the stabilization of senary FCC Al-Co-Cr-Fe-Ni-Mn high entropy alloys was investigated via a high throughput combinatorial solid-to-solid diffusion couple approach. Many off-equiatomic compositions of FCC AlCoCrFeNiMn were generated by the diffusing Al and Ni in equiatomic CoCrFeNiMn alloy, i.e.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!