Healthcare-associated infections (HAIs) are a serious threat to patients and healthcare providers. Although human factors are commonly studied in an attempt to reduce HAIs, less is known about the effect of specific facility design features on mitigating the transmission of pathogens from human to human. This facility design department aims to expand nurse leaders' knowledge and competencies in health facility design. This article discusses the state of the science in the relationship of facility design on reducing HAIs.
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http://dx.doi.org/10.1097/NNA.0000000000000039 | DOI Listing |
Environ Sci Technol
January 2025
Key Laboratory of Arable Land Conservation (Middle and Lower Reaches of Yangtse River), Ministry of Agriculture and Rural Affairs, College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China.
Though reduction of hexavalent chromium (Cr(VI)) to Cr(III) by dissolved organic matter (DOM) is critical for the remediation of polluted soils, the effects of DOM chemodiversity and underlying mechanisms are not fully elucidated yet. Here, Cr(VI) reduction and immobilization mediated by microbial byproduct (MBP)- and humic acid (HA)-like components in (hot) water-soluble organic matter (WSOM), (H)WSOM, from four soil samples in tropical and subtropical regions of China were investigated. It demonstrates that Cr(VI) reduction capacity decreases in the order WSOM > HWSOM and MBP-enriched DOM > HA-enriched DOM due to the higher contents of low molecular weight saturated compounds and CHO molecules in the former.
View Article and Find Full Text PDFFront Rehabil Sci
January 2025
Department of Occupational Therapy, Duquesne University, Pittsburgh, PA, United States.
Objective: The study explores caregiver perceptions of home programs for clients with acquired brain injury based on current clinical care after transition to the community.
Design: A qualitative descriptive study.
Setting: Within the community, post inpatient rehabilitation.
Toxicol Pathol
January 2025
Eli Lilly and Company, Indianapolis, Indiana, USA.
Nonhuman primates (NHPs) have been and remain a highly valuable animal model with an essential role in translational research and pharmaceutical drug development. Based on current regulatory guidelines, the nonclinical safety of novel therapeutics should be evaluated in relevant nonclinical species, which commonly includes NHPs for biotherapeutics. Given the practical and ethical limitations on availability and/or use of NHPs and in line with the widely accepted guiding "3Rs" (replace, reduce, and refine) principles, many approaches have been considered to optimize toxicity study designs to meaningfully reduce the number of NHPs used.
View Article and Find Full Text PDFBMJ Open
January 2025
Lancashire and South Cumbria MND Care and Research Centre, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Background: Caregivers of people with motor neuron disease (MND) face more negative consequences of caregiving than other terminal illnesses. The impact of this caregiver burden can negatively influence bereavement outcomes.
Objectives: This study aims to explore the support needs of caregivers of people with MND, the types of bereavement services they use, or the reasons for not using bereavement services, and understanding the opportunities and barriers to accessing bereavement services.
JMIR Res Protoc
January 2025
Centre of Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan.
Background: The neonatal mortality rate in Pakistan is the third highest in Asia, with 8.6 million preterm babies. These newborns require warmth, nutrition, and infection protection, typically provided by incubators.
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