Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migration, invasion and metastasis. In this review, the associations of the expression and localization of Gal-3 as well as its potential action mechanism in tumorigenesis in a variety of cancers were summarized and concluded. Gal-3 is gaining its attraction as a potential new biomarker for the diagnosis, treatment and prognosis of certain tumors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cca.2014.01.019 | DOI Listing |
Publication Analysis
Top Keywords
galectin-3 cancer
4
cancer galectin-3
4
gal-3
4
galectin-3 gal-3
4
gal-3 plays
4
plays roles
4
roles cell
4
cell proliferation
4
proliferation adhesion
4
adhesion differentiation
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!