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The Behavior of Nasopharynx Malignancies: a Retrospective Study in a Ten-Year Sample.
Neuro Endocrinol Lett
December 2024
Department of Otorhinolaryngology, University Hospital in Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic.
Objectives: Malignant tumors of the nasopharynx make up 3% of malignancies in the ENT area. The most common nasopharyngeal malignancy is nasopharyngeal carcinoma (NPC), followed by lymphomas. Other nasopharyngeal tumors are very rare.
View Article and Find Full Text PDFTMCO1-deficient mice exhibit a high incidence of otitis media associated with impaired bone homeostasis in the middle ear.
Am J Pathol
December 2024
Hearing and Speech Rehabilitation Institute, College of Special Education and Rehabilitation, Binzhou Medical University, Yantai, China. Electronic address:
Craniofacial dysmorphism, skeletal anomalies and impaired intellectual development syndrome" (CFSMR1; OMIM#213980) is characterized by craniofacial dysmorphism, skeletal anomalies, and mental retardation. However, reports of hearing issues have been limited. To investigate hearing-related aspects of CFSMR1, Tmco1 knockout mice (Tmco1) exhibiting similar symptoms to human patients were utilized in this study.
View Article and Find Full Text PDFModern combined approach to the surgical treatment of patients with post-traumatic tympanic membrane perforation due to blast injuries and eustachian tube dysfunction.
Wiad Lek
December 2024
STATE INSTITUTION ≪INSTITUTE OF OTOLARYNGOLOGY NAMED AFTER PROF. O.S. KOLOMIYCHENKO OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE≫, KYIV, UKRAINE.
Objective: Aim: To improve the effectiveness of surgical treatment for patients with post-traumatic tympanic membrane perforations and concurrent Eustachian tube dysfunction through simultaneous combined surgical methods.
Patients And Methods: Materials and Methods: We analyzed clinical and functional outcomes of 35 patients (mean age: 34 ± 10,5 years) with tympanic membrane perforations caused by acoustic and blast injuries. The patients were divided into two groups: the first group (n=17) underwent only tympanoplasty type 1, while the second group (n=18) underwent simultaneous septoplasty, inferior turbinectomy, and tympanoplasty with prolonged middle ear ventilation using a subanular Silverstein tube.
Novel Otolaryngological and Radiological Manifestations in GAPO Syndrome.
Ear Nose Throat J
December 2024
Department of Otorhinolaryngology, Al Mouwasat University Hospital, Damascus University, Damascus, Syria.
GAPO syndrome is an exceptionally-rare autosomal recessive disorder characterized by growth retardation, alopecia, pseudoanodontia, and optic abnormalities, with fewer than 60 cases reported globally. We present the first documented case in Syria, highlighting novel otolaryngological and radiological findings that expand the clinical spectrum of this syndrome. A 27-year-old male presented with chronic right-sided otalgia, unilateral conductive hearing loss, and persistent sinonasal symptoms.
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