A highly versatile synthetic strategy is described to generate multimodal and multivalent platforms based on a diethylenetriaminepentaacetic (DTPA) core. Compounds with different functionalization patterns, from mono- to pentamodal, have been prepared using robust and simple chemistry.
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http://dx.doi.org/10.1021/ol500022n | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
State Key Laboratory of Superhard Materials, College of Physics, Jilin University, Changchun 130012, China.
The abrupt drop of resistance to zero at a critical temperature is a key signature of the current paradigm of the metal-superconductor transition. However, the emergence of an intermediate bosonic insulating state characterized by a resistance peak preceding the onset of the superconducting transition has challenged this traditional understanding. Notably, this phenomenon has been predominantly observed in disordered or chemically doped low-dimensional systems, raising intriguing questions about the generality of the effect and its underlying fundamental physics.
View Article and Find Full Text PDFPLoS One
January 2025
School of Business, Xinyang Vocational College of Art, Xinyang, Henan, China.
The emergence of short video platforms has opened new avenues and opportunities for brand marketing. This paper investigates the mechanisms of brand dissemination in short videos, examining strategies for fostering brand associations to fulfill communication objectives. Drawing on signal theory, the study identifies the perceived value of short videos as the source of signals, with brand value and transparency serving as mediating factors, and brand association as the outcome.
View Article and Find Full Text PDFPLoS One
January 2025
School of Business, Anyang Normal University, Anyang, China.
The process of regional economic development is marked by a sustained exposure to external disturbances. In today's unpredictable and tumultuous global environment, such disturbances have become increasingly common, underlining the need to advance a region's economic resilience and foster adaptive mechanisms to handle environmental flux. Comparing the typical provinces in eastern, central, western and northeastern regions during the COVID-19 epidemic period, it found that the economic resilience performance of Henan Province, which is a representative of the central region, has the following characteristics.
View Article and Find Full Text PDFHum Reprod
January 2025
Institute of Genomics, Estonian Genome Centre, University of Tartu, Tartu, Estonia.
Study Question: Do polycystic ovary syndrome (PCOS), menstrual cycle phases, and ovulatory status affect reproductive tract (RT) microbiome profiles?
Summary Answer: We identified microbial features associated with menstrual cycle phases in the upper and lower RT microbiome, but only two specific differences in the upper RT according to PCOS status.
What Is Known Already: The vaginal and uterine microbiome profiles vary throughout the menstrual cycle. Studies have reported alterations in the vaginal microbiome among women diagnosed with PCOS.
PLoS One
January 2025
Department of Prosthodontics, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa.
Objective: To explore the interventions for change in oral health behaviour that are effective in improving oral health behaviours in 8 to 18-year-old children during oral health promotion.
Methods: The Joanna Briggs Institute framework of evidence synthesis for conducting a scoping review was implemented for the methodology. Included studies related to the objective, measured clinical or non-clinical outcomes, were in English, 2011-2023, and were experimental, observational or reviews.
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