AI Article Synopsis
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can lead to serious health issues if not properly treated.
- Researchers conducted a study on patients with SLE who did not respond to standard treatments and were given rituximab (RTX) to induce and maintain remission.
- The results showed that RTX significantly reduced the need for other immunosuppressive drugs and decreased the number of disease relapses, indicating it is both effective and safe for these patients.
Article Abstract
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE refractory to conventional treatment who were treated with rituximab (RTX) as remission induction therapy and maintenance. There was a significant reduction in the conventional immunosuppressive drug dose and the number of relapses of disease. RTX appeared to be effective and safe for the induction and maintenance of remission in patient with SLE refractory to conventional treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914290 | PMC |
| http://dx.doi.org/10.1155/2014/731806 | DOI Listing |
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