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Introduction/background: The Argus® II is the first retinal prosthesis approved for the treatment of patients blind from retinitis pigmentosa (RP), receiving CE (Conformité Européenne) marking in March 2011 and FDA approval in February 2013. Alpha-IMS followed closely and obtained CE marking in July 2013. Other devices are being developed, some of which are currently in clinical trials.
Sources Of Data: A systematic literature search was conducted on PubMED, Google Scholar and IEEExplore.
Areas Of Agreement: Retinal prostheses play a part in restoring vision in blind RP patients providing stable, safe and long-term retinal stimulation.
Areas Of Controversy: Objective improvement in visual function does not always translate into consistent improvement in the patient's quality of life. Controversy exists over the use of an external image-capturing device versus internally placed photodiode devices.
Growing Points: The alpha-IMS, a photovoltaic-based retinal prosthesis recently obtained its CE marking in July 2013.
Areas Timely For Developing Research: Improvement in retinal prosthetic vision depends on: (i) improving visual resolution, (ii) improving the visual field, (iii) developing an accurate neural code for image processing and (iv) improving the biocompatibility of the device to ensure longevity.
Download full-text PDF |
Source |
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http://dx.doi.org/10.1093/bmb/ldu002 | DOI Listing |
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