AI Article Synopsis
- Type 1 diabetes mellitus (T1DM) is a common chronic childhood disease caused by the autoimmune destruction of insulin-producing beta cells in the pancreas, leading to insulin deficiency.
- Most children in the US with new onset T1DM show typical symptoms like high blood sugar, with about 30% experiencing diabetic ketoacidosis (DKA), which can lead to serious neurological issues.
- The article discusses five unique cases of new onset T1DM with rare neurological symptoms and reviews relevant literature on this topic.
Article Abstract
Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in childhood and is caused by insulin deficiency resulting from the autoimmune destruction of insulin producing beta cells of the pancreas. Most children in the US with new onset T1DM present with the classic signs and symptoms of hyperglycemia and 30% with diabetic ketoacidosis (DKA). Neurologic manifestations are relatively rare and mostly include lethargy, decreased level of consciousness, and coma as a result of DKA. In this article, five cases of new onset T1DM with exceedingly rare or unreported neurologic manifestations in the pediatric age group are presented, along with a review of the literature.
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| http://dx.doi.org/10.1515/jpem-2013-0312 | DOI Listing |
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