Background: Epidemiologic studies have been inconclusive regarding the impact of coexposure to long chain polyunsaturated fatty acids (LCPUFA) and methylmercury (MeHg) from fish consumption during pregnancy on measures of fetal development.
Objectives: We evaluated the association between birth weight and prenatal maternal LCPUFA status and MeHg exposure in the Republic of Seychelles.
Methods: We measured LCPUFA in maternal whole blood collected at 28 weeks of gestation and following delivery and MeHg in maternal hair obtained at delivery. There were 230 births with complete data on birth weight and covariates. Multiple linear regression models controlled for infant sex, gestational age, maternal age, smoking during pregnancy, intrapartum weight gain, prepregnancy body mass index, maternal socioeconomic status, parity, gestational diabetes, and alcohol use during pregnancy.
Results: The average birth weight was 3252 g (range 1654-4450) and the average gestational age was 39 weeks (range 34-41). Prenatal MeHg exposure and maternal LCPUFA status were not associated with birth weight. Infant sex and length of gestation were the only predictors, with male sex and increased gestational age consistently associated with greater birth weight.
Conclusions: These findings do not support a relationship between prenatal exposure to LCPUFA and/or MeHg from fish consumption and birth weight.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951518 | PMC |
http://dx.doi.org/10.1016/j.annepidem.2014.01.002 | DOI Listing |
J Acquir Immune Defic Syndr
December 2024
Departments of Epidemiology and Anthropology, University of Washington, Seattle, WA, USA.
Background: Most infants born to women living with HIV (WLH) are HIV-exposed but uninfected exposed infants have poorer growth than HIV-unexposed uninfected children. Few large studies have compared children who are exposed (CHEU) and unexposed (CHUU) in the era of dolutegravir (DTG)-based antiretroviral treatment (ART).
Setting: Longitudinal study of mother-infant CHEU and CHUU pairs in Nairobi and Western Kenya.
PLoS One
December 2024
Department of Nursing, College of Medicine and Health Science, Woldia University, Woldia, Ethiopia.
Introduction: An unintended pregnancy refers to a situation where a pregnancy occurs either when there is no desire for a child (unwanted) or when it takes place at a time that was not anticipated (mistimed). Pregnant women infected with HIV face a two to tenfold increased risk of mortality during both pregnancy and the postpartum period compared to those who are not infected. A national level cohort study has identified that about 70 babies born HIV positive, 60% of them were from unplanned pregnancy.
View Article and Find Full Text PDFDiseases
December 2024
Centro de Investigaciones Biomédicas, Doctorado en Ciencias Biomédicas, Universidad Veracruzana, Xalapa 91190, Mexico.
Introduction: Consuming hypercaloric diets during pregnancy induces metabolic, immune, and maternal intestinal dysbiosis disorders. These conditions are transferred to the offspring through the placenta and breastfeeding, increasing susceptibility to metabolic diseases. We investigated the effect of GG supplementation on offspring maternally programmed with a hypercaloric diet.
View Article and Find Full Text PDFObjective: In preterm and very low birth weight (VLBW) infants, attention-related problems have been found to be more pronounced and emerge later as academic difficulties that may persist into school age. In response, based on three attention networks: alerting, orienting, and executive attention, we examined the development of attention functions at 42 months (not corrected for prematurity) as a follow-up study of VLBW ( = 23) and normal birth weight (NBW: = 48) infants.
Method: The alerting and orienting attention networks were examined through an overlap task with or without warning signal.
Clin Endocrinol (Oxf)
December 2024
Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Background: Osteocalcin is a metabolic active hormone, which correlates positively with bone formation and inversely with body mass index and waist circumference in adults.
Objectives: To investigate whether osteocalcin in infancy and early childhood were related to childhood growth or body composition.
Methods: A Swedish longitudinal birth cohort with blood samples from 551 children from birth until 5 years of age.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!