Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham's Dissection Manuals. Apart from this, he also produced many scientific contributions not only in the field of descriptive anatomy but also in comparative anatomy, evolution, anthropology and anthropometry. He was also a very able administrator, not only of medical schools but also in other Governmental departments, scientific journals, zoological gardens and other societies. He was also passionate about animals and gardens. He was a much respected man at both the cities of Edinburgh and Dublin. Above all, he strove for excellence with a human touch and his colleagues remembered him as a great human being. He passed away on 23 June 1909 at his home in Edinburgh.
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http://dx.doi.org/10.1007/s11845-014-1076-5 | DOI Listing |
Pediatr Infect Dis J
January 2025
From the Department of Pediatrics, Children's Mercy Hospitals and Clinics, Kansas City, Missouri.
The genetic basis of neonatal COVID-19 infection, which exhibits a range of severity, has not been investigated. We identified both shared and unique genetic variants involved in antiviral immune responses through whole exome sequencing of an infant who developed severe COVID-19 pneumonia and multisystem inflammatory syndrome and the twin brother also positive for severe acute respiratory syndrome-coronavirus-2, but with only moderate respiratory symptoms.
View Article and Find Full Text PDFCurr Probl Cancer
June 2024
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California, San Diego, CA 92093, USA; Research Service, VA San Diego Healthcare System, San Diego, CA 92161, USA. Electronic address:
Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous cancer that is characterized by distinct phenotypes based on anatomical site and etiological agents. Recently, the intratumor microbiome has been implicated in cancer pathogenesis and progression. Although it is well established that the gut microbiome varies with geographical location and is highly influenced by factors such as diet, environment, and genetics, the intratumor microbiome is not very well characterized.
View Article and Find Full Text PDFNat Commun
May 2024
Birck Nanotechnology Center, Purdue University, West Lafayette, IN, 47907, USA.
Probabilistic computing is a computing scheme that offers a more efficient approach than conventional complementary metal-oxide-semiconductor (CMOS)-based logic in a variety of applications ranging from optimization to Bayesian inference, and invertible Boolean logic. The probabilistic bit (or p-bit, the base unit of probabilistic computing) is a naturally fluctuating entity that requires tunable stochasticity; by coupling low-barrier stochastic magnetic tunnel junctions (MTJs) with a transistor circuit, a compact implementation is achieved. In this work, by combining stochastic MTJs with 2D-MoS field-effect transistors (FETs), we demonstrate an on-chip realization of a p-bit building block displaying voltage-controllable stochasticity.
View Article and Find Full Text PDFPLoS One
May 2024
Jos University Teaching Hospital, Jos, Plateau State, Nigeria.
The aetiology of mechanical bowel obstruction exhibits significant variability based on geographical location and age. In high-income countries, postoperative adhesions and hernias are frequently cited as the primary causes, whereas in low- and middle-income countries (LMCIs), hernias take precedence. Speculation exists within the surgical community regarding whether this trend has evolved in LMCIs.
View Article and Find Full Text PDFCell Mol Life Sci
May 2024
Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany.
The co-localization of the lysosomal protease cathepsin B (CTSB) and the digestive zymogen trypsinogen is a prerequisite for the initiation of acute pancreatitis. However, the exact molecular mechanisms of co-localization are not fully understood. In this study, we investigated the role of lysosomes in the onset of acute pancreatitis by using two different experimental approaches.
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