This paper deals with xenarthrans osteoderms assigned to Dasypus aff. D. novemcinctus, Euphractus sexcinctus and Cabassous sp. The material was collected in subsurface, from 0.10 to 0.60 m in the Urso Fóssil Cave, Parque Nacional de Ubajara, State of Ceará, northeastern Brazil. The ages of sediment samples from levels 4 and 5 (depths of 0.40 and 0.50 m) were determined by thermoluminescence technique, and indicated ages of 8,000 and 8,200 years BP for each layer respectively. The presence in these layers of early Holocene xenarthrans taxa can contribute to the understanding of the biotic evolution of the northwest region of Ceará during the last 10,000 years. Two of the three identified taxa still occur in the region: Dasypus novemcinctus and Euphractus sexcinctus. The Dasypodidae fauna here reported includes animals with generalist feeding habits and current wide geographical distribution. It is suggested, therefore, that the climatic and environmental conditions in the early Holocene were very similar the actual ones, and that the absence of Cabassous may be conditioned to other factors, such as anthropogenic action and loss of habitat by fragmentation of the vegetation.
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http://dx.doi.org/10.1590/0001-3765201420120029 | DOI Listing |
BMC Surg
January 2025
Health Sciences Faculty, Gedik University, Istanbul, Turkey.
Background: In this study, we aimed to investigate whether ursodeoxycholic acid (UDCA) would reduce the necessity of cholecystectomy in patients diagnosed with asymptomatic gallstones after laparoscopic sleeve gastrectomy (LSG) and in patients diagnosed with asymptomatic gallstones before LSG.
Methods: Between July 2020 and November 2022, at least 2-year follow-ups of patients who underwent LSG for obesity were retrospectively analyzed. Patients with pre-existing asymptomatic gallstones during preoperative evaluation, those with UDCA treatment (group 1), and observation group (group 2).
Antimicrob Agents Chemother
January 2025
Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, Texas, USA.
Unlabelled: Omadacycline, an aminomethylcycline tetracycline, has a low propensity to cause infection (CDI) in clinical trials. Omadacycline exhibited a reduced bactericidal effect compared with vancomycin on key microorganisms implicated in bile acid homeostasis and short-chain fatty acids (SCFAs), key components of CDI pathogenesis. The purpose of this study was to assess bile acid and SCFA changes in stool samples from healthy volunteers given omadacycline or vancomycin.
View Article and Find Full Text PDFExpert Rev Anticancer Ther
January 2025
Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy.
Small renal masses (SRM), especially those under 7 cm pose significant diagnostic challenges when using conventional imaging (CT/MRI). PET/CT with [Zr]Zr-girentuximab offers a promising alternative in this setting by enabling molecular-level imaging. The ZIRCON trial, a phase 3 multicenter study, evaluated the diagnostic accuracy of [Zr]Zr-girentuximab PET/CT in detecting clear cell renal cell carcinoma (ccRCC) in SRM.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Pharmacy, The People's Hospital of Hezhou, Hezhou, China.
Rationale: Warfarin is the most commonly used drug in patients with mechanical valve replacement. Acute liver damage after warfarin is rare but potentially harmful. We present a case of warfarin-induced gastrointestinal bleeding with liver injury, pharmacy monitoring, and its therapy.
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