Different techniques for mapping motor evoked potentials recorded from hand, upper arm, leg and mouth were analyzed. The best results were obtained when: (1) delivering constant voltage stimuli through a bipolar surface stimulator, (2) positioning the anode over the desired scalp location and the cathode 2.5 cm anterior to the anode, (3) maintaining low impedances, and (4) increasing the stimulus intensity over the theoretical motor representation area until a 500-1000 microV muscle response is achieved and then delivering the same stimulus over different scalp locations. This technique allows bilateral mapping of the different body part representations in 1-2 h. Areas so identified are small, clearly separate from each other and from the corresponding somatosensory areas.

Download full-text PDF

Source
http://dx.doi.org/10.1016/0013-4694(88)90062-4DOI Listing

Publication Analysis

Top Keywords

methodology non-invasive
4
non-invasive mapping
4
mapping human
4
human motor
4
motor cortex
4
cortex electrical
4
electrical stimulation
4
stimulation techniques
4
techniques mapping
4
mapping motor
4

Similar Publications

The rapid development and worldwide distribution of COVID-19 vaccines is a remarkable achievement of biomedical research and logistical implementation. However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. In this context, matrix-assisted laser desorption ionisation-time of flight (MALDI-ToF) mass spectrometry (MS) is globally available for fast and accurate analysis of bacteria in patient samples, offering a potentially accessible solution to identify SF vaccines.

View Article and Find Full Text PDF

3D scanner's potential as a novel tool for lymphedema measurement in mouse hindlimb models.

Sci Rep

January 2025

Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Hokkaido University, Sapporo, Japan.

Lymphedema is characterized by persistent swelling due to impaired lymphatic function and presents significant challenges in both research and clinical settings. Traditional contact-based measurement techniques such as paw thickness and circumferential measurements using calipers or silk thread are useful but limited by observer variability and measurement accuracy. Non-contact methods, including various imaging techniques, offer improvements but often at higher cost and complexity.

View Article and Find Full Text PDF

Virtual staining from bright-field microscopy for label-free quantitative analysis of plant cell structures.

Plant Mol Biol

January 2025

Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-Ku, Kumamoto, 860-8555, Japan.

The applicability of a deep learning model for the virtual staining of plant cell structures using bright-field microscopy was investigated. The training dataset consisted of microscopy images of tobacco BY-2 cells with the plasma membrane stained with the fluorescent dye PlasMem Bright Green and the cell nucleus labeled with Histone-red fluorescent protein. The trained models successfully detected the expansion of cell nuclei upon aphidicolin treatment and a decrease in the cell aspect ratio upon propyzamide treatment, demonstrating its utility in cell morphometry.

View Article and Find Full Text PDF

Current cancer screening methods are effective for detecting early stage cancers and even preventing some cancers, but their effectiveness has only been demonstrated for a handful of cancers, and for many cancers, there are no screening tests clinically available. In addition, the majority of the screening methods are not ideal, resulting in suboptimal compliance and the occurrence of preventable cancers. A screening test that is convenient, safe, accurate and that can screen for multiple cancers is an ideal screening test that would address many of the shortcomings of the current tests.

View Article and Find Full Text PDF

Background: Non-alcoholic steatohepatitis (NASH) is a serious end-stage spectrum of non-alcoholic fatty liver disease (NAFLD) with associated high risk of hepatic and extrahepatic complications. Several studies showed the significant beneficial effect of dapagliflozin on body composition, hepatic and metabolic parameters on NAFLD/NASH patients. The study aimed to investigate the efficacy and safety of dapagliflozin in both diabetic and non-diabetic biopsy-proven NASH patients; compared to pioglitazone.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!