The purposes of this study were to: (a) examine the age-related patterns of differences in height (HT), body mass (BM), percent body fat (% fat), body mass index (BMI), and skinfolds (SF) in 11- to 18-year-old wrestlers; (b) determine the coherence of direct (% fat) and indirect (BMI and SFs) indicators of adiposity in the wrestlers; and (c) compare the age-related patterns and mean values for HT, BM, BMI, subscapular, and triceps SF for the wrestlers to those of national samples of boys from the National Health and Nutrition Examination Survey (NHANES) database. One hundred thirty wrestlers were divided into 8 independent yearly age groups (AG): AG11-AG18 years. Height, BM, BMI, subscapular SF, triceps SF, medial calf SF, thigh SF, sum of SFs, and % fat were assessed. There were no differences between the wrestlers and NHANES samples for age-related patterns of BMI (0.61 and 0.63 kg·m·y), subscapular SF (0.47 and 0.37 mm·y), or triceps SF (-0.31 and -0.39 mm·y). Furthermore, the wrestlers displayed no differences in % fat between age groups. The results indicated that: (a) dissociations existed between the direct and indirect indicators of adiposity; (b) the wrestlers were similar in height but had smaller upper-body SFs when compared with NHANES samples; and (c) participation in wrestling (1-8 years) had no adverse effects on the normal age-related growth patterns for HT, but favorable effects on measures of adiposity.
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http://dx.doi.org/10.1519/JSC.0000000000000405 | DOI Listing |
Diabetes
January 2025
Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
The homeobox (HOX) family has shown potential in adipose development and function, yet the specific HOX proteins fueling adipose thermogenesis remain elusive. In this study, we uncovered the novel function of HOXC4 in stimulating adipose thermogenesis. Our bioinformatic analysis indicated an enrichment of Hoxc4 co-expressed genes in metabolic pathways and linked HOXC4 polymorphisms to metabolic parameters, suggesting its involvement in metabolic regulation.
View Article and Find Full Text PDFJ Cell Physiol
January 2025
Department of Spine, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China.
In this study, we explored the impact of different biomechanical loadings on lumbar spine motion segments, particularly concerning intervertebral disc degeneration (IVDD). We aimed to uncover the cellular milieu and mechanisms driving ossification in the nucleus pulposus (NP) during IVDD, a process whose underlying mechanisms have remained elusive. The study involved the examination of fresh NP tissue from the L3-S1 segment of five individuals, either with IVDD or healthy.
View Article and Find Full Text PDFEur J Nutr
January 2025
Department of Public Health, Section for General Practice, University of Copenhagen, Copenhagen, Denmark.
Purpose: To examine the associations and substitutions of dietary sugars [extrinsic (free) or intrinsic (non-free)] as well as dietary starch and fiber intakes for indices of body fat and cardiometabolic health.
Methods: Dietary intake was assessed at multiple times using multi-day 24-hour recalls over 18-months for indices of body fat (body fat %, waist circumference, BMI, and weight change) (n = 1066) and at baseline and 12 months for cardiometabolic outcomes (LDL, HDL, HbA1c) (n = 736). Bayesian modeling was applied to analyze the probabilistic impact of dietary carbohydrate components using credible intervals for association and substitution analyses with repeated measures random effects modeling.
Toxics
January 2025
Laboratory of Environmental Medicine and Developmental Toxicology, Guangdong Key Laboratory of Environmental Pollution and Health, College of Environment and Climate, Jinan University, Guangzhou 511443, China.
Volatile organic compounds (VOCs) are associated with obesity health risks, while the association of mixed VOCs with visceral adiposity indicators remains unclear. In this study, a total of 2015 adults from the National Health and Nutrition Examination Survey (NHANES) were included. Weighted generalized linear models, restricted cubic spline (RCS), weighted quantile sum (WQS), and Bayesian kernel machine regression (BKMR) were adopted to assess the association of VOC metabolites (mVOCs) with the visceral adiposity index (VAI) and lipid accumulation product (LAP).
View Article and Find Full Text PDFMetabolites
January 2025
Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
This study evaluated metabolites and lipid composition in the calf muscles of Type 2 diabetes mellitus (T2DM) patients and age-matched healthy controls using multi-dimensional MR spectroscopic imaging. We also explored the association between muscle metabolites, lipids, and intra-abdominal fat in T2DM. Participants included 12 T2DM patients (60.
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