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| http://dx.doi.org/10.1016/j.bjid.2013.12.002 | DOI Listing |
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Genomic Characterization of Carbapenem-Non-susceptible Clinical Isolates From Saudi Arabia Revealed a Global Dissemination of GES-5-Producing ST235 and VIM-2-Producing ST233 Sub-Lineages.
Front Microbiol
January 2022
Infectious Diseases Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Carbapenem-resistant has become a major clinical problem due to limited treatment options. However, studies assessing the trends in the molecular epidemiology and mechanisms of antibiotic resistance in this pathogen are lacking in Saudi Arabia. Here, we reported the genome characterization in a global context of carbapenem non-susceptible clinical isolates from a nationally representative survey.
View Article and Find Full Text PDFWe aimed to provide updated epidemiologic data on carbapenem-resistant Klebsiella pneumoniae in Portugal by characterizing all isolates (N = 46) recovered during 2013-2018 in a 123-bed hospital in Lisbon. We identified bla (n = 36), bla (n = 9), and bla (n = 8) carbapenemase genes and observed co-occurrence of bla and bla in 7 isolates. A single GES-5-producing isolate co-produced the extended-spectrum β-lactamase BEL-1; both corresponding genes were co-located on the same ColE1-like plasmid.
View Article and Find Full Text PDFSpread of GES-5 carbapenemase-producing Pseudomonas aeruginosa clinical isolates in Japan due to clonal expansion of ST235.
PLoS One
April 2019
Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan.
The first outbreak in Japan of GES-5 carbapenemase-producing Pseudomonas aeruginosa occurred in a long-term care facility in 2014. To assess the spread of GES-5 producing P. aeruginosa clinical isolates in medical settings in Japan, 1,476 carbapenem-resistant P.
View Article and Find Full Text PDFCarbapenem-resistant GES-5-producing Klebsiella pneumoniae in Southern Brazil.
Braz J Infect Dis
June 2014
Infectious Diseases Service, HCPA, Porto Alegre, Brazil. Electronic address:
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