Objective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD).
Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark).
Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88).
Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
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| http://dx.doi.org/10.1016/j.jcjo.2013.07.016 | DOI Listing |
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