AI Article Synopsis
- The study explored the use of CT attenuation, ADC, and SUV values to distinguish between pineal parenchymal tumors (PPTs) and germinomas, while also considering factors like age, sex, and calcification patterns.
- A total of 23 patients were retrospectively analyzed, showing no significant differences in imaging values but revealing notable age differences among tumors, with germinomas commonly affecting younger individuals.
- The findings suggest that while imaging values are not effective in differentiating these tumors, factors such as age, sex, and specific calcification patterns could provide useful diagnostic insights.
Article Abstract
Introduction: Quantitative values of CT attenuation, apparent diffusion coefficient (ADC), and standardized uptake value (SUV) were investigated for differentiation between pineal parenchymal tumors (PPTs) and germinomas. Differences in age, sex, and calcification pattern were also evaluated.
Methods: Twenty-three patients with PPTs and germinomas in 20 years were retrospectively enrolled under the approval of the institutional review board. CT attenuation, ADC, and SUV (20, 13, and 10 patients, respectively) were statistically compared between the two tumors. Differences in sex and patterns of calcification ("exploded" or "engulfed") were also examined. Mean patient ages were compared among three groups of pineoblastoma, pineal parenchymal tumor of intermediate differentiation, (PPTID) and pineocytoma and germinoma.
Results: None of the quantitative values of CT attenuation, ADC, and SUV showed significant differences between PPTs and germinomas (p > .05). However, there was a significant difference in age (p < .05) among the three groups of pineoblastoma (mean age ± standard deviation 7.0 ± 8.7 years), PPTID, and pineocytoma (53.7 ± 11.4 years) and germinoma (19.1 ± 8.1 years). Sex also showed significant differences between PPTs and germinomas (p = .039). Exploded pattern of calcification was found in 9 of 11 PPT patients and engulfed pattern in 7 of 9 patients with germinomas. No reverse pattern was observed, and the patterns of calcification were considered highly specific of tumor types.
Conclusions: None of the quantitative imaging values could differentiate PPTs from germinomas. Age, sex, and calcification patterns were confirmed useful in differentiating these tumors to some degree.
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| http://dx.doi.org/10.1007/s00234-014-1334-2 | DOI Listing |
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