The co-existence of certain peptides influenced the kinetic rate of aggregation and the lag-time of fibril formation of rbPrP. Using recently developed structural conversion assay system, peptides have been screened from bovine brain peptide library. Peptide sequences of positive components have been elucidated by mass spectrometry and chemically synthesized to confirm actions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7030918PMC
http://dx.doi.org/10.4161/pri.27961DOI Listing

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