Background: Elderly patients are under-represented in most surgical series of mitral valve surgery. The impact of preoperative heart failure (HF) on the outcomes of this subset has not been extensively studied.
Methods And Results: The study included 45,082 Medicare beneficiaries who underwent primary isolated mitral valve repair (MVP) (n=16,850) or replacement (MVR) (n=28,232) from 2000 to 2009. Medicare claims from the year before and the year of the index hospitalization were reviewed for documentation of HF to examine the operative mortality and long-term survival of patients with and without preoperative HF. Preoperative HF was present in 52.5% and 64.8% of patients who underwent repair and replacement, respectively. Duration of HF greater than 3 months was present in a significant proportion of patients (18.2% for MVP and 22.7% for MVR). Adjusted operative mortality was higher for patients with preoperative HF (MVP odds ratio [OR], 1.46; 95% confidence interval [CI], 1.21-1.78; MVR OR, 1.36; 95% CI, 1.23-1.51). Patients without preoperative HF had better long-term survival (MVP hazard ratio [HR], 2.23 [95% CI, 2.09-2.36]; MVR HR, 1.80 [95% CI, 1.73-1.86]). After adjustment, a preoperative HF diagnosis was still associated with 52% and 36% increased risk of death over the 10-year follow-up period for patients who underwent MVP and MVR, respectively. Preoperative HF duration greater than 3 months conferred an excess 28% higher risk of death on long-term follow-up compared with patients with HF less than 3 months.
Conclusions: Preoperative HF is present in a large number of elderly patients undergoing primary isolated mitral valve surgery and adversely affects their short-term and long-term survival, irrespective of procedure type (repair or replacement). The study supports the early identification of elderly patients with mitral valve disease and referral to surgery before the onset of HF.
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http://dx.doi.org/10.1016/j.jtcvs.2013.12.010 | DOI Listing |
J Surg Case Rep
January 2025
Department of Cardiac Surgery, Royal Papworth Hospital, Papworth Road, Cambridge Biomedical Campus, Cambridge, Cambridgeshire CB2 0AY, United Kingdom.
A 44-year-old gentleman presented with severe ischemic cardiomyopathy and mitral regurgitation post-inferior myocardial infarction. Echocardiography and magnetic resonance imaging revealed a dilated left ventricle with a large left ventricular aneurysm (9.3 × 9.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Cardiology, CHU Mont-Godinne UCL Namur, Yvoir, Belgium.
Post-capillary hypertension resulting from mitral regurgitation is typically considered a contraindication for single lung transplantation due to heightened risks of primary graft dysfunction. This case report highlights a 66-year-old COPD patient with severe mitral regurgitation who was deemed ineligible for surgical mitral replacement. As an alternative, transcatheter mitral valve replacement was successfully performed, resulting in the normalization of pulmonary artery pressures.
View Article and Find Full Text PDFJ Vasc Surg
January 2025
Department of Surgery, Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA. Electronic address:
Objective: Infective endocarditis (IE) is associated with significant morbidity and mortality and places patients at risk for subsequent peripheral vascular emboli. Our goals were to analyze the incidence of peripheral emboli and their associated complications and outcomes.
Methods: A retrospective single-center review of all patients with IE from 2013-2021 was performed.
Curr Cardiol Rep
January 2025
Hasselt University, Faculty of Medicine and Life Sciences / Limburg Clinical Research Centre, Agoralaan, Diepenbeek, Belgium.
Purpose Of Review: This review aims to explore the complex interplay between atrial functional mitral regurgitation (AFMR), atrial fibrillation (AF), and heart failure with preserved ejection fraction (HFpEF). The goal is to define these conditions, examine their underlying mechanisms, and discuss treatment perspectives, particularly addressing diagnostic challenges.
Recent Findings: Recent research highlights the rising prevalence of AFMR, now accounting for nearly one-third of significant mitral regurgitation cases.
Med Biol Eng Comput
January 2025
Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milan, Italy.
Performing automatic and standardized 4D TEE segmentation and mitral valve analysis is challenging due to the limitations of echocardiography and the scarcity of manually annotated 4D images. This work proposes a semi-supervised training strategy using pseudo labelling for MV segmentation in 4D TEE; it employs a Teacher-Student framework to ensure reliable pseudo-label generation. 120 4D TEE recordings from 60 candidates for MV repair are used.
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