Special topics: cardiac markers in myocarditis: cardiac transplant rejection and conditions other than acute coronary syndrome.

Clin Lab Med

Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Gray 5 Chemistry, Boston, MA 02114, USA. Electronic address:

Published: March 2014

AI Article Synopsis

  • Blood biomarkers like troponin T and I are crucial for diagnosing acute coronary syndromes and heart failure.
  • Elevated troponin levels can also occur in conditions like myocarditis and transplant rejection, which can lead to misdiagnosis.
  • Even in the absence of acute coronary syndrome or heart failure, high troponin levels can provide important diagnostic or prognostic information.

Article Abstract

The utility of blood biomarkers of cardiac myocyte damage such as troponin T and I in the evaluation of acute coronary syndromes and heart failure is well established. However, some of these markers may also be elevated in other conditions, such as myocarditis, cardiac transplant rejection, and several other conditions. Recognizing this phenomenon is essential to avoid misdiagnosis of acute coronary syndromes. Furthermore, identifying an elevated troponin level in patients without acute coronary syndrome or heart failure may often have diagnostic or prognostic significance.

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Source
http://dx.doi.org/10.1016/j.cll.2013.11.004DOI Listing

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