Macrophages gain a partner at the table: epidermal cells digest peripheral dendritic debris in Drosophila.

Neuron

Department of Biochemistry and Molecular Biology at MD Anderson Cancer Center, Houston, TX 77030, USA; Neuroscience Program, Graduate School of Biomedical Sciences, Houston, TX 77030, USA; Genes and Development Program, Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Electronic address:

Published: February 2014

In this issue of Neuron, Han et al. (2014) develop powerful methods to visualize phagocytosis of Drosophila peripheral sensory neuron dendrites. Remarkably, epidermal cells rather than professional phagocytes are the primary mediators of debris clearance, using both familiar and new molecular players.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963384PMC
http://dx.doi.org/10.1016/j.neuron.2014.01.029DOI Listing

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