We report the results of a screening study on pregnant women and early onset neonatal group B streptococcal infections in Sofia, Bulgaria, July 2009-July 2010. Women were studied for risk factors at delivery, intrapartum antibiotic prophylaxis (lAP) and outcome for the newborns. All GBS positive women who had risk factors at delivery gave birth to newborns with neonatal infection despite the IAP given in 50% of the cases. The majority of the GBS positive women who had no risk factors at delivery gave birth to healthy newborns although only 32% of them received IAP However 11% of the GBS positive women without risk factors delivered children with neonatal infection. We consider that IAP should be given to all GBS positive women to prevent from neonatal infection. The dominant GBS serotypes were ll, 11 and la. The isolates were 100% susceptible to penicillin, cefazolin, cefotaxime, vancomycin and 91.66% susceptible to erythromycin and clindamycin, the resistant strains being from the MLSB phenotype.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia.
NIHR Open Res
October 2023
Department of Malaria and Neglected Tropical Disease Research, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Background: Cutaneous leishmaniasis (CL) is a skin neglected tropical disease, with an estimated 40,000 new cases each year in Ethiopia. CL causes ulcers, nodules, and plaques on the skin, and in some instances the destruction of the nasopharyngeal mucosa and cartilage. Some CL lesions may heal spontaneously, whilst other lesions may require therapies which are associated with discomfort, adverse effects, prolonged treatment, and a frequent lack of a complete response.
View Article and Find Full Text PDFGlobal burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.
Front Public Health
January 2025
Sanitation Teaching and Research Section, Department of Health Service, Naval Medical University, Shanghai, China.
Background: Norovirus remains a significant viral cause of waterborne and foodborne gastroenteritis outbreaks and epidemics worldwide. The burden of norovirus extends across different income settings.
Methods: Leveraging secondary data from the 2021 Global Burden of Diseases Study, our analysis spanned the period from 1990 to 2021 to assess the burden of norovirus-associated diseases (NADs).
colonization and undernutrition in infants in rural eastern Ethiopia - a longitudinal community-based birth cohort study.
Front Public Health
January 2025
Department of Animal Sciences, Global Food Systems Institute, and Emerging Pathogens Institute, University of Florida, Gainesville, FL, United States.
Background: is associated with environmental enteric dysfunction (EED) and malnutrition in children. infection could be a linchpin between livestock fecal exposure and health outcomes in low-resource smallholder settings.
Methods: We followed a birth cohort of 106 infants in rural smallholder households in eastern Ethiopia up to 13 months of age.
Predictors of insecticide-treated nets utilization among children under five years in refugee settlements in Uganda: analysis of the 2018-2019 Uganda Malaria Indicator Survey.
Malar J
January 2025
Department of Geography, Geo-Informatics and Climatic Sciences, Makerere University, P.O Box 7062, Kampala, Uganda.
Background: Despite significant distribution of insecticide-treated net (ITNs) by the Government of Uganda to refugees, malaria is major cause of mortality and morbidity among children under five years in refugee settlements. This highlights the persistent challenges and complexities surrounding malaria control and prevention efforts in these settings. Studies that focus on the determinants of ITN utilization among children under five years in refugee settlements in Uganda are not available.
View Article and Find Full Text PDFTheoretical impact of a bedside decision-making tool on antibiotic use for suspected neonatal healthcare-associated infection: an observational study.
BMC Pediatr
January 2025
Department of Pediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Background And Objectives: Healthcare-associated infections (HAI) are a leading contributor to morbidity and mortality in hospitalised neonates. Diagnosing neonatal HAI is challenging owing to non-specific symptoms and lack of definitive diagnostic markers, contributing to high rates of inappropriate antibiotic use. This study evaluated the theoretical impact of implementing a bedside tool for decision-making on antibiotic length of therapy (LOT).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!