AI Article Synopsis
- This study shows that graphene nanoribbons modified with carboxyphenyl groups and bonded with Gd(3+) ions are effective as contrast agents in MRI.
- They significantly enhance imaging performance with contrast abilities (relaxivity) that are up to 16 times greater for T1-weighted and 21 times greater for T2-weighted imaging compared to existing clinical agents.
- This innovation could lead to improvements in medical imaging techniques and diagnostics.
Article Abstract
The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd(3+) ions can serve as a high-performance contrast agent (CA) for applications in T1- and T2-weighted magnetic resonance imaging (MRI) with relaxivity (r1,2) values outperforming currently-available clinical CAs by up to 16 times for r1 and 21 times for r2.
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| http://dx.doi.org/10.1039/c3nr06026h | DOI Listing |
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