AI Article Synopsis
- The study analyzed the bacterial community structure of oral biofilms in young healthy adults at various maturation stages (1, 3, 5, 9, and 14 days) using samples from 32 participants.
- Researchers found a high diversity of bacteria, categorizing them into 8 phyla and 15 classes, with significant individual differences accounting for 35% of the total variability in microbiota.
- They identified three distinct clusters of subjects based on specific and mutually exclusive groups of bacteria present in their oral biofilms.
Article Abstract
In the present study we aimed to analyze the bacterial community structure of oral biofilms at different maturation stages in young healthy adults. Oral biofilms established on membrane filters were collected from 32 human subjects after 5 different maturation intervals (1, 3, 5, 9 and 14 days) and the respective phylogenetic diversity was analyzed by 16S rDNA amplicon sequencing. Our analyses revealed highly diverse entire colonization profiles, spread into 8 phyla/candidate divisions and in 15 different bacterial classes. A large inter-individual difference in the subjects' microbiota was observed, comprising 35% of the total variance, but lacking conspicuous general temporal trends in both alpha and beta diversity. We further obtained strong evidence that subjects can be categorized into three clusters based on three differently occurring and mutually exclusive species clusters.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913613 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087449 | PLOS |
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