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Endoscopic ultrasound navigated application of botulinum toxin in severe esophageal motility disorder.
Clin J Gastroenterol
December 2024
Clinic of Internal Medicine-Gastroenterology, University Hospital in Martin, Jessenius Faculty of Medicine, Martin, Slovakia.
The use of botulinum toxin in the therapy of esophageal motility disorders is reserved for elderly and comorbid patients considered risky for endoscopic or surgical treatment. However, there is a lack of data on the treatment of motility disorders outside the Chicago classification.We present the case of a 56-year-old patient with dysphagia and non-cardial chest pain (Eckardt 8).
View Article and Find Full Text PDFHigh prevalence of esophageal motility disorders in patients with rheumatologic diseases.
Dis Esophagus
November 2024
Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, Center for Gastrointestinal Biology and Disease, Chapel Hill, NC, USA.
Article Synopsis
- * A study of 289 adults showed that 58% had esophageal motility disorders, with various types identified, despite normal barium swallow results in half of these cases.
- * Specific rheumatic conditions affected the likelihood of esophageal dysmotility, with lower rates in those with psoriatic arthritis and varying odds for rheumatoid arthritis and scleroderma.
Lung cancer metastasis-induced distal esophageal segmental spasm confirmed by individualized peroral endoscopic myotomy: A case report.
World J Gastrointest Surg
October 2024
Department of Endoscopy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fujian Branch of Fudan University Shanghai Cancer Center, Fuzhou 350014, Fujian Province, China.
Background: Peroral endoscopic myotomy (POEM) has been widely performed as a standard treatment for achalasia; however, its efficacy and safety for treating distal esophageal segmental spasms induced by cancer metastasis remain unknown.
Case Summary: A 72-year-old male was referred to our hospital and complained of progressive dysphagia for two years. Endoscopy revealed a 2 cm long segment esophageal stenosis with intact mucosa and normal cardia.
Achalasia: Diagnosis and Management.
Surg Clin North Am
February 2025
University of Massachusetts Chan Medical School, Baystate Medical Center, Springfield, MA, USA. Electronic address:
Achalasia is an incurable condition of the esophagus involving the inflammation and degeneration of inhibitory neurons of the lower esophageal sphincter (LES) resulting in failure of the LES to relax. Typical symptoms of achalasia are dysphagia, retrosternal chest pain, regurgitation, and weight loss. Three studies are typically required for the diagnosis of achalasia: barium swallow, high-resolution esophageal manometry, and esophagogastroduodenoscopy.
View Article and Find Full Text PDFDiagnosis and Management of Noncardiac Chest Pain.
Gastroenterol Hepatol (N Y)
October 2024
Division of Gastroenterology, Mayo Clinic Florida, Jacksonville, Florida.
Noncardiac chest pain is a challenging condition often encountered by primary care providers, emergency medicine physicians, and gastroenterologists. It is frequently accompanied by persistent symptoms, diagnostic uncertainty, decreased quality of life, and high health care burden. Gastroesophageal reflux disease is the most common esophageal cause followed by functional chest pain, and at least half of patients with noncardiac chest pain have psychiatric comorbidities such as anxiety or depression.
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