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A novel example of double 6-exo-trig heterocyclization: nitrile conversion to new anticancer active (HeLa cells) primary amine ionic liquids. | LitMetric
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A novel example of double 6-exo-trig heterocyclization: nitrile conversion to new anticancer active (HeLa cells) primary amine ionic liquids.

Denis Prodius Hamid Saeed Shah Jamshed Iqbal Anastasia Macaeva Anatoli Dimoglo George E Kostakis Nicolas Zill Fliur Macaev Annie K Powell

Chem Commun (Camb)

Institute of Nanotechnology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.

Published: May 2014

Conversion of nitriles under mild conditions leads to a new class of primary amines, including room temperature ionic liquids, acting as efficient anticancer agents.

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 Source
http://dx.doi.org/10.1039/c3cc49759cDOI Listing

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