Oncolytic viruses are novel immunotherapeutic agents that appear to mediate potent antineoplastic effects in both preclinical and clinical settings. Recent studies demonstrate that manipulating the mechanisms whereby cancer cells die in the course of oncolytic virotherapy has potential to boost anticancer immune responses.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912054PMC
http://dx.doi.org/10.4161/onci.27138DOI Listing

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