One of the prioritized objectives of psychophysiological support for long-duration space missions is to strengthen professional reliability of cosmonauts. Operator's reliability is dependent as on skillfulness, so individual work style. PILOT-1 and VIRTU methods were used to study individual psychological characteristics and operator's strategy during project MARS500. The established two individual work styles (IWSs), i.e. control and search, reflect different types of reacting to stress. Combined analysis of these data and results of the "Mirror coordinograph" test showed invariance of IWSs no matter whether a task is complicated or simple. Operators demonstrating the "control" strategy are characterized by high initial mobilization readiness. Their reliability demands great physiological resources (high "cost"). Initial mobilization and physiological "cost" are lower in operators demonstrating the "search" work style. Dependent on the level of mobilization and motivation, their efficacy, in terms of quality and reliability specifically, is unstable in nature.

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