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The Use of Dietary Supplements for the Management of Adverse Effects of Treatment in Children and Adolescents with Leukemia: A Scoping Review.
Nutr Cancer
December 2024
School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Acute lymphoblastic leukemia is the most prevalent form of leukemia in children and adolescents. Despite high survival rates due to advanced treatments, these therapies often result in significant treatment-related adverse effects. This scoping review explores dietary supplementation strategies for managing these adverse effects in pediatric leukemia patients.
View Article and Find Full Text PDFPerioperative risk factors for osteoporosis after radical gastrectomy for gastric cancer.
BMC Surg
December 2024
Department of Surgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Boramae-ro 5-20, Dongjak-gu, Seoul, 07061, Republic of Korea.
Background: Osteoporosis, a frequent complication of gastrectomy, increases with age, and the average age of gastric cancer patients continues to rise. This study aims to analyze perioperative factors of osteoporosis after radical gastrectomy.
Materials And Methods: This retrospective cohort study included patients who underwent dual-energy-X-ray absorptiometry after gastrectomy due to gastric cancer between 2016 and 2019 at Seoul Boramae Medical Center.
Identification of a bacteria P450 enzyme from B. megaterium H-1 with vitamin D C-25 hydroxylation capabilities.
Enzyme Microb Technol
December 2024
College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China.
Calcidiol (25(OH)VD) and calcitriol (1α,25(OH)VD) are active vitamin D with high medicinal value, which can maintain calcium and phosphorus balance and treat vitamin D deficiency. Microbial synthesis is an important method to produce high-value-added compounds. It can produce active vitamin D through the hydroxylation reaction of P450, which can reduce the traditional chemical synthesis steps, and greatly improve the production efficiency and economic benefits.
View Article and Find Full Text PDFSerum Vitamin D in Children with Hemophilia A and Its Association with Joint Health and Quality of Life.
Hematol Rep
November 2024
Department of Pediatrics, Faculty of Medicine, Beni-Suef University, Beni-Suef 62521, Egypt.
: Hemophilia A is an X-linked recessive illness produced by a deficiency of coagulation factor VIII. This study aimed to evaluate serum vitamin D in hemophilic pediatric patients and its correlation with joint health and quality of life. : This case-control study was performed on ninety children under the age of 18 years old and separated into two groups: study group of 45 children with hemophilia A and control group of 45 healthy children at an outpatient pediatric hematology clinic at the Beni-Suef University hospitals.
View Article and Find Full Text PDFPrevalence of Vitamin D Deficiency With Biochemical Abnormalities in Children Undergoing Vitamin D Testing.
Clin Endocrinol (Oxf)
December 2024
Department of Medicine, University of Auckland, Auckland, New Zealand.
Objective: Vitamin D deficiency (VDD) in children can cause hypocalcaemia and rickets, but the prevalence of these complications and the 25-hydroxyvitamin D (25OHD) concentrations below which they arise is uncertain. We investigated this in children (< 18 years) with 25OHD measurements.
Design, Measurement And Patients: We obtained 25OHD results from the regional laboratory database, alongside albumin-adjusted serum calcium (aCa), parathyroid hormone (PTH) and alkaline phosphatase (ALP) within 6 months of the index 25OHD.
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