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Examining the Biophysical Properties of the Inner Membrane of Gram-Negative ESKAPE Pathogens.
J Chem Inf Model
January 2025
Department of Biochemistry, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador A1C 5S7, Canada.
The World Health Organization has identified multidrug-resistant bacteria as a serious global health threat. Gram-negative bacteria are particularly prone to antibiotic resistance, and their high rate of antibiotic resistance has been suggested to be related to the complex structure of their cell membrane. The outer membrane of Gram-negative bacteria contains lipopolysaccharides that protect the bacteria against threats such as antibiotics, while the inner membrane houses 20-30% of the bacterial cellular proteins.
View Article and Find Full Text PDFGenetics of sorghum: grain quality, molecular aspects, and drought responses.
Planta
January 2025
Department of Plant Sciences, University of the Free State, Bloemfontein, South Africa.
Sorghum kernel composition is a crucial characteristic that determines its functional qualities. The total protein content of sorghum grain increases under drought stress, but starch, protein digestibility, and micronutrient contents decrease. Sorghum (Sorghum bicolor L.
View Article and Find Full Text PDFDevelopment of a Highly Nutritious Vegetable Beverage Based on Kurugua (Sicana odorifera) and Chia Oil (Salvia hispanica).
Plant Foods Hum Nutr
January 2025
Facultad de Ciencias Químicas, Dirección de Investigaciones, Universidad Nacional de Asunción, P.O. 1055, San Lorenzo, Paraguay.
Concerns over malnutrition, synthetic additives and post-harvest waste highlight the need for innovation in food technology, turning towards underutilized crops. Plant-based beverages offer sustainable dietary alternatives and the increasing demand for such products makes the exploration of native crops particularly relevant. This study focuses on the development of a beverage derived from the native South American fruit kurugua (Sicana odorifera), combined with chia oil (Salvia hispanica L.
View Article and Find Full Text PDFBioconversion of mustard oil cake for production of lipase, optimization and direct immobilization from solid-state fermentation extract.
Prep Biochem Biotechnol
January 2025
Department of Physical Science, Sant Baba Bagh Singh University, Jalandhar, Punjab, India.
Fungal lipases are the leading industrial biocatalyst due to their broad applications, but high cost limits their commercial usage. The low-cost agri-residues substrates can reduce the cost of lipase production. However, the compatibility of agri-residue with fungal species, recovery process of lipase and stability of the enzyme are crucial steps.
View Article and Find Full Text PDFChrysanthemum extract mitigates high-fat diet-induced inflammation, intestinal barrier damage and gut microbiota disorder.
Food Funct
January 2025
Institute of Food Nutrition and Quality Safety, College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
An effective intervention for obesity without side effects is needed. Chrysanthemum may be the preferred choice due to its influence in the improvement of glycolipid metabolism. This study assessed the efficacy of chrysanthemum and its flavonoids in mitigating high-fat diet (HFD) induced obesity, focusing on the integrity of the intestinal barrier, inflammation, and gut microbiota.
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