Halitosis is a common complaint of one third of the population. It is commonly known as 'bad breath'. The causes of halitosis can both be intraoral (90%) as well as extraoral (10%). Malodor of oral etiology results from the oral cavity itself. Non oral etiology may include various systemic diseases and use of certain drugs. Halitosis can act as a biomarker for various systemic diseases. Organoleptic examination, gas chromatography and portable sulfide monitors are the common methods of measurement of halitosis. Brushing twice daily with tongue cleaning can sufficiently manage halitosis in majority of the population while antimicrobial oral rinses can be prescribed to the non respondents. Necessary investigations and treatment should follow for those having extra oral cause of halitosis.
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http://dx.doi.org/10.4103/2231-0762.86374 | DOI Listing |
Nephrol Nurs J
January 2025
Professor of Pharmacy Practice, Clinical Pharmacotherapy Specialist, Nephrology & Dialysis, Arnold &Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY.
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Department of Head & Neck Surgery, Singapore General Hospital, Singapore, Republic of Singapore.
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View Article and Find Full Text PDFSpec Care Dentist
January 2025
Department of Pediatric and Preventive Dentistry, Centre for Dental Education and Research, AIIMS, New Delhi, India.
Renal tubular acidosis (RTA) is a group of disorders in which there is an alteration in acid-base homeostasis because of the impairment of nephrons to excrete hydrogen ions or reabsorb bicarbonate ions, resulting in chronic metabolic acidosis. RTA is an important cause of rickets, particularly 'resistant rickets'. Dental manifestations frequently reported in patients with RTA include enamel hypoplasia and amelogenesis imperfecta, affecting permanent dentition.
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College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan-si, Gyeonggi-do, Republic of Korea.
Dose adjustments of direct-acting oral anticoagulants (DOACs) for atrial fibrillation are based on pivotal clinical trials assessing their effectiveness and safety in controlled settings. However, the appropriateness of these dosing strategies in real-world practice is uncertain. The purpose of this study is to compare the effectiveness and safety of dose-specific DOACs with those of warfarin.
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State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
The EGFR-driven angiogenesis is crucial in solid tumors, particularly through the delivery of biomolecules via extracellular vesicles (EVs), but the mechanism by which EGFR regulates EV cargo is still unclear. First, cell co-culture and murine tumor models were employed to examine the impact of EGFR overexpression on the pro-angiogenic properties of small EVs (sEVs) derived from oral squamous cell carcinoma (OSCC). Small RNA sequencing was then used to compare the miRNA profiles of OSCC-sEVs with and without EGFR overexpression, followed by functional enrichment and motif analyses of the differentially expressed miRNAs.
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