We evaluated the performance and the cost of toxigenic culture using a commercial chromogenic medium (CDIF) for 538 stool specimens. Compared with real-time PCR, this method was found to detect an additional 9% of positive specimens and result in 61% reduction in material costs, with a trade-off increase in turnaround time of 1 day.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911300PMC
http://dx.doi.org/10.1128/JCM.03113-13DOI Listing

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