AI Article Synopsis
- The study analyzed how H7N9 influenza viruses attach to the respiratory tract across various animals, including ferrets, macaques, mice, pigs, and guinea pigs.
- The attachment pattern in macaques, mice, and some pigs/guinea pigs was found to be more similar to that in humans compared to ferrets.
- This research enhances understanding of different animal models used for studying influenza viruses.
Article Abstract
We determined the pattern of attachment of the avian-origin H7N9 influenza viruses A/Anhui/1/2013 and A/Shanghai/1/2013 to the respiratory tract in ferrets, macaques, mice, pigs, and guinea pigs and compared it to that in humans. The H7N9 attachment pattern in macaques, mice, and to a lesser extent pigs and guinea pigs resembled that in humans more closely than the attachment pattern in ferrets. This information contributes to our knowledge of the different animal models for influenza.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993775 | PMC |
| http://dx.doi.org/10.1128/JVI.03190-13 | DOI Listing |
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