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Regioselective C2 sulfonylation of indoles mediated by molecular iodine. | LitMetric
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Regioselective C2 sulfonylation of indoles mediated by molecular iodine.

Praewpan Katrun Charoensak Mueangkaew Manat Pohmakotr Vichai Reutrakul Thaworn Jaipetch Darunee Soorukram Chutima Kuhakarn

J Org Chem

Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand.

Published: February 2014

A facile and general method for regioselective C2 sulfonylation reaction of indoles mediated by iodine is described. The 2-sulfonylated products were obtained up to 96% yield under mild reaction conditions (room temperature, 2 h).

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 Source
http://dx.doi.org/10.1021/jo402831kDOI Listing

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