Purpose: To describe the efficacy of episcleral brachytherapy in a choroidal melanoma and circumscribed hemangioma arising in both eyes of the same patient.
Case Report: We present the case of a 47 year old man who presented decreased visual acuity a few months preceding initial consult. On fundoscopy, he presented a melanotic lesion in the right eye, and a red-orange choroidal mass in the macular area of the left eye.
Material And Methods: B scan-ultrasound, fluorescein, and indocyanine green angiography, confirmed the diagnosis of choroidal melanoma in the right eye, and circumscribed choroidal hemangioma in the left eye. Episcleral brachytherapy with (125)I was performed in both eyes consecutively.
Results And Conclusions: Bilateral episcleral brachytherapy successfully treated both tumors, preserving the eyes and useful visual function.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899632 | PMC |
http://dx.doi.org/10.5114/jcb.2013.38523 | DOI Listing |
Am J Ophthalmol
December 2024
Department of Radiation Oncology (L.C., M.S., H.L., Y.C., W.S.), Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:
Purpose: Uveal melanoma (UM) represents the most prevalent and aggressive intraocular malignancy in adults. This study examined the outcomes of patients diagnosed with high-risk UM who underwent fractionated stereotactic radiosurgery (fSRS) treatment utilizing a novel Linear Accelerator (LINAC)-based frameless technique.
Design: Retrospective, interventional case series.
Ocul Oncol Pathol
December 2024
Cairo University Ocular Oncology Service, Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.
Am J Ophthalmol Case Rep
December 2024
Duke University Eye Center, 2351 Erwin Road, Durham, NC, 27710, USA.
Purpose: Patients with conjunctival squamous cell carcinoma that present with persisting disease or recurrence following topical chemotherapy and/or surgery especially when invading the sclera are challenging to treat. Herein, we describe the use of high-dose-rate (HDR), FDA-cleared, yttrium-90 (Y) plaque brachytherapy for such lesions.
Observation: Three cases of invasive conjunctival squamous cell carcinoma that had exhibited a poor response or recurrence following topical chemotherapy and/or surgery are described.
Curr Treat Options Oncol
July 2024
Hacettepe University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey.
Uveal melanoma is the most common primary ocular tumor in adults. With the evidence demonstrating that episcleral plaque brachytherapy (EPB) has similar survival rates as enucleation in the Collaborative Ocular Melanoma Study (COMS), eye-sparing treatments have come to the fore today. External radiotherapy techniques (proton beam radiotherapy and stereotactic radiosurgery/fractionated stereotactic radiosurgery) are an important treatment option for globe-sparing treatments.
View Article and Find Full Text PDFOphthalmol Sci
March 2024
The Department of Ocular Tumor, Orbital Disease, and Ophthalmic Radiation Therapy, The New York Eye Cancer Center, New York, New York.
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