Purpose: To describe a case of recurrent, bilateral panuveitis caused by the BRAF proto-oncogene inhibitor vemurafenib.
Methods: Case report.
Results: A 25-year-old woman developed bilateral panuveitis and macular edema after initiating treatment with the BRAF enzyme inhibitor vemurafenib for stage IV cutaneous melanoma. The patient was successfully treated with sub-Tenon triamcinolone injections along with cessation of the medication.
Conclusions: Panuveitis is a potential adverse effect of vemurafenib. Good communication with oncology is necessary, in case the medication needs to be discontinued.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5301/ejo.5000423 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Demography in Swiss paediatric uveitis: a retrospective cohort study.
J Ophthalmic Inflamm Infect
December 2024
Department of Ophthalmology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 24, Zurich, 8091, Switzerland.
Introduction: Paediatric uveitis is a rare disease. It can affect any segment and have various etiologies, including infectious, autoimmune, and masquerade diseases. The pupose of this study is to analyse and present the demographic data in paediatric uveitis in a Swiss cohort.
View Article and Find Full Text PDFPattern of Uveitis in a Tertiary Care Eye Hospital Setting in Pakistan: A Comprehensive Analysis.
Ocul Immunol Inflamm
December 2024
Oculoplasty Department, LRBT Tertiary Teaching Eye Hospital, Korangi, Karachi, Pakistan.
Purpose: To determine the patterns of uveitis evident in patients presenting at the Uveitis Department of a tertiary care eye hospital located in Karachi, Pakistan.
Study Design: Prospective cross-sectional study.
Location And Duration Of Study: This study was conducted at Layton Rahmatullah Benevolent Trust (LRBT) Tertiary Teaching Eye Hospital-Korangi, Karachi, Pakistan from August 2020 to July 2023.
Uveitis in paediatric Behçet disease: a large multicentric Italian cohort.
Ther Adv Musculoskelet Dis
December 2024
Rheumatology Unit, ERN ReCONNET Center, Meyer Children's Hospital IRCCS, Florence, Italy.
Background: Behçet disease (BD) is a rare disease in childhood and its uveitis may lead to blindness if not properly treated.
Objectives: We aim to describe a cohort of paediatric BD patients with uveitis.
Design: This is a multicentric retrospective study.
Sympathetic ophthalmia (SO) is a rare, bilateral, granulomatous, panuveitis following perforating trauma or surgical intervention in one eye. Here, and to the best of knowledge, we report the first case of SO following an evisceration surgery in Pakistan. A 32-year-old, Pakistani, female presented with pain and decreased visual acuity in her right eye, at Civil Hospital, Karachi, 1 week after an evisceration surgery was performed on her left eye, following corneal perforation due to unresolved keratitis.
View Article and Find Full Text PDFCBL syndrome presenting with severe EBV infection and panuveitis masquerade.
Eur J Ophthalmol
November 2024
Department of Ophthalmology, IHU FOReSIGHT, Hôpital Universitaire Pitié-Salpêtrière, Sorbonne Université, Paris, France.
Article Synopsis
- This case report discusses a 35-month-old boy with CBL syndrome who experienced life-threatening Epstein-Barr virus (EBV) infections and rod-cone dystrophy (RCD) that appeared similar to severe panuveitis.
- Genetic testing indicated a pathogenic variant related to CBL syndrome, leading to complications including encephalitis and severe eye inflammation.
- The report emphasizes the importance of considering RCD in CBL syndrome patients with unexplained eye inflammation and suggests using carbonic anhydrase inhibitors as a treatment for cystoid macular edema.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!