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Undifferentiated Pleomorphic Sarcoma with Reactive Eccrine Syringofibroadenoma: A Case Report.
Dermatopathology (Basel)
October 2024
Southern Regional Hospital of Tropical Dermatology-Trang Province, Department of Medical Services, Ministry of Public Health, Trang 92000, Thailand.
Article Synopsis
- Undifferentiated pleomorphic sarcoma (UPS) is a highly aggressive soft tissue cancer with a poor prognosis, often diagnosed only after metastasis has occurred.
- Eccrine syringofibroadenoma (ESFA) is a rare skin lesion linked to eccrine ducts, with one subtype arising as a reaction to other inflammatory or neoplastic conditions.
- A case study is presented involving a 70-year-old man who had both UPS and reactive ESFA, highlighted by a specific skin lesion on his palm characterized by atypical cells and distinctive epidermal changes.
Intravascular Papillary Endothelial Hyperplasia in Association with Eccrine Angiokeratomatous Hamartoma.
Indian J Dermatol
January 2024
From the Department of Dermatology, Jeonbuk National University Medical School, Jeonju, South Korea.
Eccrine angiokeratomatous hamartoma is a variant of eccrine angiomatous hamartoma. Histopathologically, it shows both features of eccrine angiomatous hamartoma with components of angiokeratoma. Eccrine angiokeratomatous hamartoma is extremely rare.
View Article and Find Full Text PDFConcurrent presentation of porocarcinoma and basal cell carcinoma arising on a capillary malformation: a case report.
Arch Craniofac Surg
October 2023
Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Porocarcinoma (PC) and basal cell carcinoma (BCC) are distinct skin cancers. Few studies have documented the occurrence of two concurrent types of skin cancers, and to the best of our knowledge, this represents the inaugural report of such a coexisting lesion arising from a capillary malformation. Herein, we report a case of concurrent PC and BCC presenting with capillary malformation.
View Article and Find Full Text PDFAutosomal dominant genodermatoses in adults being heralded by superimposed skin lesions in children.
Am J Med Genet C Semin Med Genet
June 2023
Department of Dermatology, Medical Center-University of Freiburg, Freiburg, Germany.
Article Synopsis
- Autosomal dominant skin disorders can exhibit pronounced mosaic involvement in neonates, stemming from early loss of heterozygosity in the embryo shortly after fertilization.
- Some syndromes, like Brooke-Spiegler and Hornstein-Knickenberg, show early-onset symptoms that can foreshadow later, more widespread manifestations of the disorder.
- Conditions like glomangiomatosis and Darier disease demonstrate that neonatal mosaic lesions can be early indicators of nonsegmental skin issues emerging much later in life.
An Unusual Case of a Scrotal Porocarcinoma and Review of the Literature.
Am J Dermatopathol
January 2023
Departments of Pathology, and.
Porocarcinomas are rare tumors derived from the acrosyringium and eccrine ducts, which most commonly occur on the lower extremities or head and neck region in older adults. Microscopically, they invariably demonstrate continuity with the epithelium, showing downgrowth of broad anastomosing bands with more infiltrative intradermal cords and nests of pleomorphic tumor cells with ductal lumina; an associated poroma may also be seen. We report an unusual case of a porocarcinoma arising on the scrotum of a 55-year-old man.
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