Objectives: This study was conducted to review the validity of the need for the application of the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) to household chemical products in Korea. The study also aimed to assess the severity of health and environmental hazards of household chemical products using the GHS.
Methods: 135 products were classified as 'cleaning agents and polishing agents' and 98 products were classified as 'bleaches, disinfectants, and germicides.' The current status of carcinogenic classification of GHS and carcinogenicity was examined for 272 chemical substances contained in household chemical products by selecting the top 11 products for each of the product categories. In addition, the degree of toxicity was assessed through analysis of whether the standard of the Republic of Korea's regulations on household chemical products had been exceeded or not.
Results: According to GHS health and environmental hazards, "acute toxicity (oral)" was found to be the highest for two product groups, 'cleaning agents and polishing agents', and 'bleaches, disinfectants, and germicides' (result of classification of 233 household chemical products) at 37.8% and 52.0% respectively. In an analysis of carcinogenicity assuming a threshold of IARC 2B for the substances in household chemical products, we found 'cleaning agents and polishing agents' to contain 12 chemical substances and 'bleaches, disinfectants, and germicides' 11 chemical substances.
Conclusion: Some of the household chemical products were found to have a high hazard level including acute toxicity and germ cell mutagenicity, carcinogenicity, and reproductive toxicity. Establishing a hazard information delivery system including the application of GHS to household chemical products in Korea is urgent as well.
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http://dx.doi.org/10.1186/2052-4374-25-11 | DOI Listing |
Environ Pollut
December 2024
RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, the Czech Republic. Electronic address:
Indoor dust contains various endocrine-disrupting contaminants, yet the effect drivers of observed glucocorticoid activity are completely unknown. This study conducted an effect-directed analysis using orthogonal fractionation to identify effect drivers of glucocorticoid activity in indoor dust. After the detection of bioactivity using a human cell line stably transfected with a reporter gene, the sample underwent parallel HPLC fractionations with octadecyl, pentafluorophenyl, and aminopropyl columns to obtain orthogonal fractions.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Botanical Garden, Institute of Nature and Environmental Technology, Kanazawa University, Kakumamachi, Kanazawa, Ishikawa, 920-1192, Japan.
Quaternary ammonium compounds (QACs), ecotoxic organic chemicals linked to multidrug resistance, are being used increasingly, for example to prevent the transmission of infections such as covid-19, in households, hospitals, and industry. To understand the locations, fluctuations, and fractions of QACs entering sewers, we monitored 14 QACs (benzalkonium chloride [BAC]-C8, C10, C12, C14, C16, and C18; dialkyldimethylammonium chloride [DDAC]-C8, C10, and C12; alkyltrimethylammonium chloride [ATAC]-C12, C16, and C18; benzethonium chloride; and cetylpyridinium chloride), and a disinfectant (chlorhexidine) in influent at four Japanese sewage treatment plants (STPs) five times throughout a year. Mass inflows were relatively stable throughout the year, indicating that the recent seasonal covid-19 epidemic did not greatly influence them.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Department of Chemical Engineering, Bogazici University, TR-34342 Istanbul, Türkiye.
A new member is incorporated into the SERS active materials family daily as a consequence of advances in materials science. Furthermore, it has been demonstrated that MXenes, which display remarkable physicochemical characteristics, are also encompassed within this family. This Review offers a comprehensive and systematic assessment of the potential of MXene structures in the context of SERS applications.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Physics, University of Dhaka, Dhaka, 1000, Bangladesh.
This research presents an explicit analysis of the effects of sintering temperature (T) on the structural, morphological, magnetic, and optical properties of CuMgFeO nanoferrites synthesized via the sol-gel method. To accomplish it, Cu-Mg ferrite NPs were sintered at temperatures ranging from 300 to 800 °C in increments of 100 with a constant holding duration of 5 h. Thermogravimetric analysis was used to observe the degradation of organic components and the thermally stable zone of the material.
View Article and Find Full Text PDFTrop Med Health
December 2024
Graduate School of Public Health, St. Luke's International University, CCA 5th Floor, 3-6-2 Tsukiji, Chuo-Ku, Tokyo, 104-0045, Japan.
Background: Malaria remains the leading cause of under-five morbidity and mortality in low- and middle-income countries. Sleeping under mosquito nets, especially insecticide-treated nets (ITNs), is one of the best ways to prevent malaria as they form a physical and chemical barrier against mosquitoes. Therefore, the present study aimed to assess not only mosquito net use, but also how environmental factors, specifically land surface temperature, contribute to malaria prevention among households with children under 5 years of age in Lao PDR.
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