Hydrogen-bond-mediated aglycone delivery: focus on β-mannosylation.

Org Lett

Department of Chemistry and Biochemistry, University of Missouri-St. Louis , One University Boulevard, St. Louis, Missouri 63121, United States.

Published: February 2014

O-Picoloyl groups at remote positions can mediate the course of glycosylation reactions by providing high facial selectivity for the H-bond-mediated attack of the glycosyl acceptor. A new practical method for the stereoselective synthesis of β-mannosides at ambient temperature is presented.

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Source
http://dx.doi.org/10.1021/ol403396jDOI Listing

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