AI Article Synopsis
- The catalytic hydroamination of alkenes with amines can efficiently produce valuable chiral amines from basic starting materials.
- Mild copper-catalyzed methods are emphasized for the targeted synthesis of both straight-chain and branched chiral amines.
- This approach offers a promising strategy for creating complex molecules in a straightforward manner.
Article Abstract
Adding value: The catalytic hydroamination of alkenes with amines holds promise to rapidly deliver value-added chiral amines from simple and accessible starting materials. The use of mild, Cu-catalyzed electrophilic amination strategies for the regioselective preparation of both linear and chiral branched amines is highlighted.
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| http://dx.doi.org/10.1002/anie.201309262 | DOI Listing |
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