A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi-lipid vesicle. This composite system enables a large loading capacity for hydrophobic drugs.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092317 | PMC |
| http://dx.doi.org/10.1039/c3lc51260f | DOI Listing |
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