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Numerical Simulation of Fluid Shear Stress Distribution in Microcracks of Trabecular Bone.
Appl Bionics Biomech
January 2025
Beijing Institute of Technology, School of Aerospace Engineering, Beijing 100081, China.
Bone is one of the hardest tissues in the human body, but it can undergo microcracks under long-term and periodic mechanical loads. The Newton iterative method was used to calculate the steady state, and the effects of different inlet and outlet pressures, trabecular gap width and height, and microcrack's depth and width on the fluid shear stress (FSS) were studied, and the gradient of FSS inside the microcrack was analyzed. The results show that the pressure difference and trabecular gap heigh are positively correlated with the FSS (the linear correlation coefficients were 0.
View Article and Find Full Text PDFThe effect of physical cues on platelet storage lesion.
Hematology
December 2025
Department of Blood Transfusion, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Background: Platelet concentrates play an important role in clinical treatment such as platelet function disorders and thrombocytopenia. In the process of preparation and storage of platelets, centrifugation, leukofiltration, and agitation will cause morphological changes and impaired function of platelets, which is associated with the increase of platelet transfusion refractoriness, and named as platelet storage lesion (PSL).
Method: This paper proposes three major operations (centrifugation, agitation, and leukofiltration) that platelets experience during the preparation and storage process, to explore the effect of physical cues on PSL.
Dietary inulin supplementation improves meat quality and off-flavor of duck meat referring to regulated muscle fiber types and antioxidant capacity.
Food Chem X
January 2025
College of Food Science & Engineering, Qingdao Agricultural University, Qingdao 266109, China.
This study aimed to evaluate the effects of dietary inulin (0-30 g/kg) on duck meat, muscle fiber types, meat quality, antioxidant ability, Low-field nuclear magnetic resonance, amino acid and off-flavor. These results indicated that inulin promoted the conversion of type II to type I muscle fibers. Compared with the control group, supplementation with 20 g/kg inulin reduced ( < 0.
View Article and Find Full Text PDFA prospective observational study on intracranial pressure management: A comparison of three ultrasound techniques.
J Clin Neurosci
January 2025
Department of Ultrasonic Medicine, Fudan University Affiliated Huashan Hospital, No 12, Middle Wulumuqi Road, Shanghai 200040, China. Electronic address:
Objective: This prospective observational study aimed to assess the effectiveness of B-mode ultrasound, color-coded Doppler, and shear-wave elastography in predicting intracranial pressure (ICP) and their capability to evaluate the efficacy of ICP lowering therapy.
Materials And Methods: Forty-eight neuro-critical care patients were enrolled and categorized into 2 groups based on ICP measurements obtained through external ventricular drainage: the intracranial hypertension (IH) and normal ICP groups. The optic nerve (ON) sheath diameter (ONSD), end diastolic velocity, peak systolic velocity, resistance index of the central retinal artery (CRA), and Young's modulus (YM) of the ON were recorded after external ventricular drainage placement and following ICP lowering treatment in the IH group.
Discovering non-associated pressure-sensitive plasticity models with EUCLID.
Adv Model Simul Eng Sci
January 2025
Department of Mechanical and Process Engineering, Institute for Mechanical Systems, ETH Zürich, Zürich, 8092 Switzerland.
We extend (EUCLID Efficient Unsupervised Constitutive Law Identification and Discovery)-a data-driven framework for automated material model discovery-to pressure-sensitive plasticity models, encompassing arbitrarily shaped yield surfaces with convexity constraints and non-associated flow rules. The method only requires full-field displacement and boundary force data from one single experiment and delivers constitutive laws as interpretable mathematical expressions. We construct a material model library for pressure-sensitive plasticity models with non-associated flow rules in four steps: (1) a Fourier series describes an arbitrary yield surface shape in the deviatoric stress plane; (2) a pressure-sensitive term in the yield function defines the shape of the shear failure surface and determines plastic deformation under tension; (3) a compression cap term determines plastic deformation under compression; (4) a non-associated flow rule may be adopted to avoid the excessive dilatancy induced by plastic deformations.
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