Piwi-interacting RNAs (piRNAs) originate from genomic regions dubbed piRNA clusters. How cluster transcripts are selected for processing into piRNAs is not understood. We discuss evidence for the involvement of chromatin structure and maternally inherited piRNAs in determining their fate.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053809 | PMC |
| http://dx.doi.org/10.1186/gb4154 | DOI Listing |
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