AI Article Synopsis
- The study investigated the relationship between intrabolus pressure (IBP) and esophagogastric junction (EGJ) relaxation pressure in dysphagia patients using high-resolution manometry (HRM).
- The research involved 22 dysphagia patients and analyzed 220 individual swallows categorized by the Chicago classification, focusing on peristalsis patterns and discrepancies between IBP and integrated relaxation pressure (IRP).
- Results showed no significant correlation between the pattern of peristalsis and bolus transit; the authors suggest further studies are needed to explore this relationship.
Article Abstract
Background/aims: High-resolution manometry (HRM), with a greatly increased number of recording sites and decreased spacing between sites, allows evaluation of the dynamic simultaneous relationship between intrabolus pressure (IBP) and esophagogastric junction (EGJ) relaxation pressure. We hypothesized that bolus transit may occur when IBP overcomes integrated relaxation pressure (IRP) and analyzed the relationships between peristalsis pattern and the discrepancy between IBP and IRP in patients with dysphagia.
Methods: Twenty-two dysphagia patients with normal EGJ relaxation were examined with a 36-channel HRM assembly. Each of the 10 examinations was performed with 20 and 30 mmHg pressure topography isobaric contours, and findings were categorized based on the Chicago classification. We analyzed the relationships between peristalsis pattern and the discrepancy between IBP and IRP.
Results: Twenty-two patients were classified by the Chicago classification: 1 patient with normal EGJ relaxation and normal peristalsis, 8 patients with intermittent hypotensive peristalsis and 13 patients with frequent hypotensive peristalsis. A total of 220 individual swallows were analyzed. There were no statistically significant relationships between peristalsis pattern and the discrepancy between IBP and IRP on the 20 or 30 mmHg isobaric contours.
Conclusions: Peristalsis pattern was not associated with bolus transit in patients with dysphagia. However, further controlled studies are needed to evaluate the relationship between bolus transit and peristalsis pattern using HRM with impedance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895612 | PMC |
| http://dx.doi.org/10.5056/jnm.2014.20.1.74 | DOI Listing |
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