[Oxygen-binding capacities of hemoglobin and nitric oxide].

Ross Fiziol Zh Im I M Sechenova

Published: May 2013

The analysis of the literature and our own results indicates that a nitric oxide carries out a role the allosteric effector of hemoglobin, changing its affinity to oxygen and defining a condition of oxygen transport blood function. It is important point for modification of functional properties of hemoglobin and its participation in the flow of oxygen in tissues, which plays an important role in development of disadaption reactions at stress and decreased bioactivity of the nitric oxide at the endothelial dysfunction. These findings give possiblity to creat the new ways to correct hypoxical conditions through influence on oxygen-binding properties of the blood and activity of L-arginin-NO system.

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