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The Apoprotein E4 isotype does not affect the severity of COVID-19 infection and other flu-like syndromes.
J Med Microbiol
January 2025
Departamento de Bioqumica e Imunologia, Instituto de Cincias Biolgicas, Universidade Federal de Minas Gerais.
Apolipoprotein E (ApoE), especially the ApoE4 isotype, is suggested to influence the severity of respiratory viral infections; however, this association is still unclear. The presence of allele ε4 impacts the development of flu-like syndromes. This study aimed to evaluate the impact of the Apo E4 isoform on the severity and duration of flu-like syndromes, including the coronavirus disease COVID-19.
View Article and Find Full Text PDFImpact of Weight Loss on Testosterone Levels: A Review of BMI and Testosterone.
Cureus
December 2024
Internal Medicine and Family Medicine, Larkin Community Hospital Palm Springs Campus, Miami, USA.
The purpose of this review is to explore the relationship between weight loss (WL), specifically reductions in body mass index (BMI), and increases in testosterone levels. Obesity and excess body fat are linked to reduced testosterone levels, which can lead to metabolic dysfunctions, reduced libido, and diminished muscle mass. To attain this purpose, this review will summarize current evidence on how weight reduction interventions, including dietary changes, exercise, and bariatric surgery, affect testosterone production in overweight and obese individuals.
View Article and Find Full Text PDFSex and gender differentials in the prevalence of obesity and its association with multimorbidity among reproductive-aged individuals in India.
Front Public Health
January 2025
Department of Health Research, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.
Introduction: The increase in the prevalence of obesity has become a common public health issue worldwide, with low- and middle-income countries (LMICs) like India witnessing an equal rise. It makes a considerable contribution to chronic diseases as it is a major risk factor for other chronic illnesses. Multimorbidity, or the presence of two or more chronic illnesses, is becoming more common in LMICs, resulting in poor health outcomes.
View Article and Find Full Text PDFBackground: Sarcopenia is a progressive, generalized disease of skeletal muscle characterized by a loss of muscle strength and muscle mass. The combination of obesity and sarcopenia is called sarcopenic obesity. Because of the aging of the population in many countries around the world, sarcopenia and sarcopenic obesity are a challenge for global health policy.
View Article and Find Full Text PDFBMI gain and dietary characteristics are risk factors of MASLD in non-obese individuals.
Sci Rep
January 2025
Center for Health Promotion, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
This longitudinal observational study aimed to evaluate whether cardiometabolic factors and dietary characteristics are determinants of metabolic dysfunction-associated steatotic liver disease (MASLD) in non-obese individuals (body mass index [BMI] < 25 kg/m²). The study was conducted at the Japanese Red Cross Society Kyoto Daiichi Hospital. Clinical data were longitudinally recorded at annual health checks.
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