DNA is a nanowire in nature which chelates Ni ions and forms a conducting chain in its base-pairs (Ni-DNA). Each Ni ion in Ni-DNA exhibits low (Ni(2+)) or high (Ni(3+)) oxidation state and can be switched sequentially by applying bias voltage with different polarities and writing times. The ratio of low and high oxidation states of Ni ions in Ni-DNA represents a programmable multistate memory system with an added capacitive component, in which multistate information can be written, read, and erased. This study also indicates that the biomolecule-based self-organized nanostructure can be used as a template for nanodevice fabrication.
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http://dx.doi.org/10.1021/nl404601s | DOI Listing |
Cancers (Basel)
January 2025
Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Cancer cells must reprogram their metabolism to sustain rapid growth. This is accomplished in part by switching to aerobic glycolysis, uncoupling glucose from mitochondrial metabolism, and performing anaplerosis via alternative carbon sources to replenish intermediates of the tricarboxylic acid (TCA) cycle and sustain oxidative phosphorylation (OXPHOS). While this metabolic program produces adequate biosynthetic intermediates, reducing agents, ATP, and epigenetic remodeling cofactors necessary to sustain growth, it also produces large amounts of byproducts that can generate a hostile tumor microenvironment (TME) characterized by low pH, redox stress, and poor oxygenation.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Joint International Research Laboratory of Information Display and Visualization, School of Electronic Science and Engineering, Southeast University, Nanjing 210096, China.
This study presents a facile one-pot synthesis method to fabricate BiFeO-BiFeO-BiO heterojunction photocatalysts with controllable compositions and pure phases. Three different binary heterojunctions (BiFeO/BiFeO, BiFeO/BiO, and BiFeO/BiO) and a ternary BiFeO/BiFeO/BiO heterojunction were formed, all exhibiting significantly enhanced photocatalytic performance for the degradation of methylene blue (MB) and phenol under visible light irradiation, outperforming the individual compositions. Notably, the BiFeO/BiFeO heterojunction achieved the highest degradation efficiency (93.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
College of Resources, Sichuan Agricultural University, Chengdu 611130, China.
Previous studies have demonstrated that γ-Aminobutyric acid (GABA) effectively alleviates heavy metal stresses by maintaining the redox balance and reducing the accumulation of reactive oxygen species (ROS). However, little is known about the role of GABA on programmed cell death (PCD) under Cd treatments in plants. The present study investigated the effects of GABA on Cd-induced PCD in two species, oilseed rape (, ), and black mustard (, ).
View Article and Find Full Text PDFPolymers (Basel)
December 2024
School of Packaging and Materials Engineering, Hunan University of Technology, Zhuzhou 412007, China.
Pyrene (Pr) was used to improve the electrochemical and electrochromic properties of polythiophene copolymerized with 3,4-ethylenedioxythiophene (EDOT). The corresponding product, poly(3,4-ethylenedioxythiophene-co-Pyrene) (P(EDOT-co-Pr)), was successfully synthesized by electrochemical polymerization with different monomer concentrations in propylene carbonate solution containing 0.1 M lithium perchlorate (LiClO/PC (0.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong 10120, Thailand.
A single-component flavin-dependent halogenase, AetF, has emerged as an attractive biocatalyst for catalyzing halogenation. However, its flavin chemistry remains unexplored and cannot be predicted due to its uniqueness in sequence and structure compared to other flavin-dependent monooxygenases. Here, we investigated the flavin reactions of AetF using transient kinetics.
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