Introduction And Hypothesis: This prospective randomized study aimed to compare the safety and efficacy of the TVT-Secur (TVT-S) with the trans vaginal obturator tape (TVT-O) for the treatment of stress urinary incontinence.
Methods: We set out to enroll 136 patients in our study. 106 patients with stress urinary incontinence were randomized to either the TVT-S (n = 56) or TVT-O (n = 50) procedure. Patients were evaluated postoperatively at 2 months and 1 year. Our primary outcome was objective cure measured by the cough test. Secondary outcomes of subjective symptoms, questionnaires, pain scores, complications, and urodynamic studies were also included. Statistical analysis was by Chi-squared, Kruskal-Wallis, Wilcoxon, and Fisher's exact tests as appropriate. P values of <0.05 were considered significant.
Results: Objective cure rates were better for TVT-O compared with TVT-S at 1 year (86 % and 63 % respectively, p = 0.01). Subjective cure rates were 88 % for TVT-O and 63 % for TVT-S. Quality of life scores through questionnaires improved in both groups and were not statistically different. Initial post-operative groin pain was more prevalent in the TVT-O group; however, this resolved quickly with time.
Conclusion: TVT-O was superior to TVT-S in the objective cure of stress urinary incontinence at 1-year follow-up.
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http://dx.doi.org/10.1007/s00192-013-2312-7 | DOI Listing |
Front Public Health
January 2025
School of Obstetrics and Childcare, Faculty of Medicine, Universidad Andrés Bello, Santiago, Chile.
Background: Urinary incontinence (UI), which can be classified as stress, urgency, or mixed, represents a public health problem that mainly affects adult women. This study aimed to determine the prevalence, association of sociodemographic and obstetric factors with the types of UI as well as the perceived impact on quality of life of women attending primary health facilities in the Tacna region from Peru.
Methods: A quantitative, non-experimental, correlational, and cross-sectional study was conducted.
Int J Med Sci
January 2025
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Nephrotoxicity remains a significant concern associated with tyrosine kinase inhibitors, such as dasatinib (DASA). Previous studies have shown that DASA can induce renal tubular cell death, contributing to its nephrotoxic effects. In contrast, naringenin (NGN) is known for its antioxidant and anti-inflammatory properties.
View Article and Find Full Text PDFCell Physiol Biochem
December 2024
Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo 11884, Egypt.
Background/aims: Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy, defined as diabetes diagnosed in the second or third trimester, often asymptomatic. This study investigates the therapeutic potential of olive leaf extracts and stem cells in mitigating GDM-induced complications, particularly focusing on renal function, oxidative stress, and pancreatic cell regeneration.
Methods: Measurements were made in gravid female rats with or without intraperitoneal administration of Streptozotocin (35 mg/kg body weight).
Urol J
December 2024
Department of Urology, The 3rd Affiliated Hospital of Chengdu Medical College, Pidu District People's Hospital, Chengdu, China.
Purpose: Working during non-traditional hours is becoming more prevalent in modern societies and presents a significant hurdle to an individual's circadian rhythm. We examined the bladder health of shift workers in the United States by analyzing information obtained from the National Health and Nutrition Examination Survey.
Materials And Methods: National Health and Nutrition Examination Survey (NHANES) datasets from 2005 to 2010 were utilized.
Phytomedicine
December 2024
School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, PR China; College of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, PR China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xi'an 712046, PR China; Shaanxi Key Laboratory of Research and Application of"Taibai Qi Yao", Xianyang 712046, PR China. Electronic address:
Background: Southern Schisandra is the dried and matured fruit of Schisandra sphenanthera Rehd. et Wils. in the family of Magnoliaceae; Traditional medicine reports that Schisandra sphenanthera has astringent and astringent properties, benefiting qi and promoting the production of body fluid, tranquilising the heart and calming the mind; it is clinically utilized for prolonged cough, thirst due to injury of the body fluid, internal heat and thirst, palpitation and insomnia, etc.
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