Two unusual dibenzofurans, preussiafurans A-B (1-2), together with six known compounds have been isolated from the fungus Preussia sp. occurring in Enantia chlorantha Oliv. The structures were established on the basis of 1D and 2D NMR spectroscopy and MS analysis. Compounds 1-4 showed antiplasmodial activity against erythrocytic stages of chloroquine-resistant Plasmodium falciparum (NF54) and moderate cytotoxicity on L6 cell lines with IC50 values of 8.67 and 14.8 μM, respectively.
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http://dx.doi.org/10.1016/j.fitote.2014.01.003 | DOI Listing |
BMC Complement Med Ther
September 2023
SDG #03 Group - Good Health and Well-being, Landmark University, Ipetu Road, PMB 1001, Omu-Aran, 251101, Nigeria.
J Ethnopharmacol
June 2023
Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, HD1 3DH, United Kingdom. Electronic address:
Ethnopharmacology Relevance: Alstonia boonei De Wild. (stem bark), Anacardium occidentale L. (stem bark), Azadirachta indica A.
View Article and Find Full Text PDFFront Biosci (Elite Ed)
September 2022
Department of Microbiology and Virology, Institute of Medicine, RUDN University, 117198 Moscow, Russia.
Background And Aim: Antibiotics' resistance is the leading cause of complications in the treatment of urinary tract infections. This study aimed to screen the antimicrobial potential of 8 plants from Cameroon against multi-resistant uropathogenic (MRU) bacteria and to investigate their antibioresistance reversal properties.
Method: Bioactive compounds were extracted from leaves of , , and ; barks of and barks and seeds of and leaves and seeds of using water and ethanol as solvents.
J Ethnopharmacol
October 2022
Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon. Electronic address:
Ethnopharmacological Relevance: Enantia chlorantha is traditionally used to treat various ailments including rickettsia fever, cough and wounds, typhoid fever, infective hepatitis, jaundice, and urinary tract infections.
Aim Of The Study: To isolate the antibacterial constituents of the hydro-ethanolic extract of the stem bark of E. chlorantha (ECB) and to evaluate the antibacterial and antibiotic-modifying activities of ECB and its constituents against the multidrug-resistant (MDR) phenotypes.
Open Vet J
April 2022
Department of Microbiology and Virology, Institute of Medicine, RUDN University, Moscow, Russia.
Background: The evaluation of medicinal plants' toxicity is a prerequisite prior to their usage. The vertebrate models used for this purpose are often the object of ethical consideration. Though invertebrate models including have demonstrated the ability to be used to assess the toxicity of various products.
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