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Affective responses in adults with severe obesity living or not with a mental disorder during two consecutive 6-min walking exercises.
Encephale
March 2025
École de kinésiologie et des sciences de l'activité physique (EKSAP), Faculté de médecine, Université de Montréal, Montréal, QC, Canada; Centre de recherche de l'Institut universitaire en santé mentale de Montréal, Montréal, QC, Canada. Electronic address:
Objectives: Affective response during physical activity can partly determine its adherence in adults with severe obesity living or not with a mental disorder. This study examined affective responses to physical activity in adults with severe obesity living or not with a mental disorder.
Materials And Methods: Two groups (24 adults with severe obesity, body mass index=44.
Factors Predicting Spontaneous Regression in Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Diseases.
Clin Lymphoma Myeloma Leuk
February 2025
Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Kanagawa, Japan.
Background: Other iatrogenic immunodeficiency-associated lymphoproliferative diseases (OIIA-LPDs) occur in patients taking immunosuppressive drugs (ISDs) for autoimmune diseases, such as rheumatoid arthritis and have been suggested to be associated with Epstein-Barr virus (EBV) infection. Although some patients regress spontaneously upon discontinuation of ISDs, factors predicting spontaneous regression (SR) remain controversial. Therefore, we conducted a retrospective observational study of the clinical characteristics and factors associated with treatment response, prognosis, and SR in patients diagnosed with OIIA-LPD.
View Article and Find Full Text PDFObesity substantially impacts rheumatic and musculoskeletal diseases: time to act.
Ann Rheum Dis
March 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Obesity is a major health problem and risk factor for many chronic health conditions, including rheumatic and musculoskeletal diseases (RMDs). Around 7 in 10 adults with RMD live overweight or with obesity. Obesity not only increases the risk of developing RMDs.
View Article and Find Full Text PDFFeasibility and impact of an expanded upper extremity musculoskeletal health for musicians (MHM) program on arm and hand pain in musicians.
J Hand Ther
March 2025
Leon Root, MD Motion Analysis Laboratory, Department of Rehabilitation, Hospital for Special Surgery, New York, NY, USA. Electronic address:
Background: This easibility cohort study follows a prior randomized control pilot trial that examined the feasibility and impact of a formal Musculoskeletal Health for Musicians (MHM) program. In this follow-up study, an expanded program was designed to target hand and arm pain by adding exercises for the wrist, elbow, forearm, and hand intrinsic muscles. The MHM program combines education with exercise instruction to prevent pain and injury in musicians.
View Article and Find Full Text PDFPredictors of Radiation Resistance and Novel Radiation Sensitizers in Head and Neck Cancers: Advancing Radiotherapy Efficacy.
Semin Radiat Oncol
April 2025
Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA.. Electronic address:
Radiation resistance in head and neck squamous cell carcinoma (HNSCC), driven by intrinsic and extrinsic factors, poses a significant challenge in radiation oncology. The key contributors are tumor hypoxia, cancer stem cells, cell cycle checkpoint activation, and DNA repair processes (homologous recombination and non-homologous end-joining). Genetic modifications such as TP53 mutations, KRAS mutations, EGFR overexpression, and abnormalities in DNA repair proteins like BRCA1/2 additionally affect radiation sensitivity.
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