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Acute Myocardial Injury in Intracerebral Hemorrhage: Smoking Gun or Innocent Bystander.
J Am Heart Assoc
January 2025
Department of Neurology with experimental Neurology (Klinik und Hochschulambulanz für Neurologie mit experimenteller Neurologie), Charité-Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.
Spin caloritronics as a probe of nonunitary superconductors.
Sci Adv
January 2025
Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70803-4001, USA.
Superconducting spintronics explores the interplay between superconductivity and magnetism, sparking substantial interest in nonunitary superconductors as a platform for magneto-superconducting phenomena. However, identifying nonunitary superconductors remains challenging. We demonstrate that spin current driven by thermal gradients sensitively probes the nature of the condensate in nonunitary superconductors.
View Article and Find Full Text PDFPrevalence and clinical features of interstitial lung disease in patients with psoriasis.
BMC Pulm Med
December 2024
Department of Dermatology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Background: Despite the autoimmune nature of psoriasis, the potential association between psoriasis and interstitial lung disease (ILD) remains underexplored. This study aimed to investigate the frequency and clinical features of ILD in patients with psoriasis and propose a new conceptual framework of "ILD associated with psoriasis".
Methods: A retrospective analysis of 117 patients with psoriasis was conducted, excluding those without chest imaging prior to methotrexate or biologic use and those with other comorbidities leading to ILD.
Gunshot Residue Deposition With and Without Firearm Suppressors (Silencers).
Am J Forensic Med Pathol
October 2024
Department of Pathology, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI.
Forensic pathologists recognize the importance of estimating the range of fire for gunshot entrance wounds. Classically described ranges of fire include contact, close range, medium (or intermediate) range, and indeterminate (or distant) range. The presence or absence of gunshot residue (smoke/soot and/or gunpowder) and the characteristics of the gunshot residue are evaluated in order to estimate the range of fire.
View Article and Find Full Text PDFmiR-4448/Girdin/Akt/AMPK axis inhibits EZH2-mediated EMT and tumorigenesis in small-cell lung cancer.
Cancer Med
October 2024
Department of Respiratory Medicine, Saitama Medical Center, Saitama Medical University, Kawagoe-shi, Saitama, Japan.
Article Synopsis
- Small-cell lung cancer (SCLC) displays high levels of EZH2, which promotes a process called epithelial-mesenchymal transition (EMT), increasing the cancer's invasive ability.
- Researchers investigated the relationship between microRNAs (specifically miR-4448) and EZH2 in SCLC, discovering that the downregulation of EZH2 leads to increased miR-4448 expression, which appears to inhibit tumor growth and EMT.
- miR-4448 targets the girdin gene to suppress its expression, reducing Akt phosphorylation, which subsequently enhances the phosphorylation of AMPK and EZH2, ultimately preventing EZH2-mediated EMT and tumorigenesis in SCLC.
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